Key Questions

Question 1

List a Few Antiarrhthmics that prolong QT

Answer 1

Sotalol - Amiodarone - Quinidine (A class I)

Question 2

What Classes of Drugs increase the QT Interval/ Precipitate TdP?

Answer 2

AntiArrhythmics AntiMicrobials Antipsychotics Antidepressants Other drugs include Zolmitriptan and Sumitriptan, and Methadone

Question 3

List a Few Antimicrobials that prolong QT

Answer 3

Erythro and Clarithyro + the “flouroquinolones” drugs

Question 4

List a Few Antidepressants that prolong QT

Answer 4

SSRI’s and Amitriptyline

Question 5

Two Antipsycotic drugs that Prolong QT

Answer 5

Haloperidol and Quetiapine

Question 6

What is the Acronym for Enzyme Inhibitors

Answer 6

Sickfaces.com

Question 7

List the enzyme inhibitors

Answer 7

Sodium Valproate

Isoniazid (TB drug)

Cimetidine (h2 blocker)

Ketoconazole

Fluconazole (antifungals)

Fluoxetine

Alcohol

Chloramphenicol

Erythromycin

Sulphonamides

Ciprofloxacin

Omeprazole

Metronidazole

Question 8

Clinical Signs of Hyperkalaemia?

Answer 8

the image + MURDER

Muscle cramps

Urine abnormalitites

Respiratory distress

EKG Changes

Reflexes impaired

Question 9

Important Drugs causing hypokalemia

Answer 9

Drugs causing Hypokalemia

Salbutamol

Digoxin

Aldosterone antagonists.

Theophylline

Question 10

Important drugs causing hyperkalemia?

Answer 10

1. Heparin
2. NSAIDS
3. Aldosterone Antagonists
4. ACE Inhibitors
5. Laxatives containging vitamin K (movicol and fybrogel)

Question 11

What is the normal reference range for Potassium?

Answer 11

serum potassium is 3.5 - 5.3 mmol/L

Question 12

Clinical signs of hyperkalemia