key stuff Flashcards

(32 cards)

1
Q

worst type of thyroid cancer

A

anaplastic

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2
Q

thyroid cancer that spreads via blood

A

follicular

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3
Q

thyroid cancer associated with MEN

A

medullary

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4
Q

medullary cancers originate from what cells

A

parafolicular C cells

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5
Q

what do medullary/c cell cancers release

A

calcitonin

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6
Q

what does calcitonin do

A

reduces blood calcium

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7
Q

which 2 thyroid cancers have same cellular structure so hard to differentiate via FNA

A

follicular adenoma and carcinoma

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8
Q

which cancer occurs in iodine rich areas

A

papillary

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9
Q

which cells and hormone lead to increased blood Ca+

A

parathyroid releases PTH = inc blood calcium

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10
Q

stimulation of adrenal medulla to release adrenalin

A

pre-ganglionic sympathetic fibres

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11
Q

cells of parathyroid

A

chief cells

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12
Q

chief cells release

A

parathyroid hormone

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13
Q

c cells found where

A

follicle of thyroid

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14
Q

what can cause direct aldosterone release from adrenal cortex

A

high K+ blood

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15
Q

high Na+ and high glucose

A

cushings

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16
Q

what is low in addisons

17
Q

addison bloods will show

A

low glucose
low sodium
high potassium
hypotension

18
Q

cells that release epinephrin

19
Q

release of glucocorticoids into blood results in what

A

proteins and fats converted to glucose
glucose goes up
immune system supressed

20
Q

what effect does aldosterone have

A

retention of sodium and water

incr BP

21
Q

glucagon produced by what cells

A

alpha in pancreas

22
Q

glucagon does what

A

trigger gluconeogenesis and glucogenolysis = increase in blood glucose (opposite role of insulin)

23
Q

most common thyroid cancer

24
Q

papillary spreads how

A

lymph (can present with goitre and lymphadonopathy)

25
investigation for addisions
short synactin test (give ACTH to see if cortisol goes)
26
most common hormone to be treated from pituitary tumour
1) ACTH | 2) GH
27
2 types of diabetes incibidus
cranial/neurogenic: dont produce ADH (desmopressin - fake vasopressin) Nephrotic: dont have receptors on kidneys
28
cushings test
over night dexomethasone (is a synthetic cortisol so see if it suppresses cortisol production)
29
test for growth hormone
insulin stress test
30
drugs for hyperthroidism
carbimazole | PTU
31
3 places addisons can be originating
primary: adrenal secondary: pituitary
32
hormone secreting lung tumours
small cell is ACTH | squamous cell is PTH