Kidd (009) Blood Group System

Question 1

Notorious for causing hemolytic transfusion reaction (delayed type)

Answer 1

Kidd (Jk)

Question 2

Gene location of Kidd

Answer 2

Chromosome 18q

Question 3

Antithetical antigens of kidd

Answer 3

Jka and Jkb

Question 4

Well developed at birth as early as

Answer 4

11th week: jka
7th week: jkb

Question 5

Not found in platelets and WBCS.
Unaffected by chloroquine, DTT,AET,glycine-acid EDTA.

Answer 5

Kidd antigens

Question 6

They demonstrate dosage, are often weak, and are found in combination with other antibodies, all of which make them difficult to detect.

Answer 6

Kidd antibodies

Question 7

Made in response to pregnancy or transfusion

Answer 7

Kidd antibodies

Question 8

More frequently encountered Kidd antibody

Answer 8

Anti Jka

Question 9

Enzyme treatment of Kidd antibodies

Answer 9

Enhanced by LISS, PEG, increased Ab:Ag ratio

Question 10

Cause of Delayed Hemolytic Transfusion Reaction

Answer 10

Secondary/ Anamnestic Immune Response

Question 11

Increased bilirubin
Hemosiderinuria
DAT positive
Unexplained depletion of Hgb and Hct

Answer 11

Delayed Hemolytic Transfusion Reaction

Question 12

Urea transporter

Answer 12

Kidd glycoprotein

Question 13

Jka/Jkb is located at what position?

Answer 13

280

Question 14

Most abundant Kidd blood among Polynesian

Answer 14

Null phenotype

Question 15

Elute anti-Jk3, anti-Jka indicating that genes are expressed but only VERY WEAK

Answer 15

Dominant type Jk(a-b-)

Question 16

IgG
Phenotype as Jk(a-b-)
React optimally at IAT
ENZYME ENHANCED
HTR: Yes ( severe immediate and delayed)
HDN: Yes (mild)

Answer 16

Anti-Jk3

Question 17

Bacteria that were able to convert Jk(b-) cells to Jk(b+)

Answer 17

Enterococcus faecium and Micrococcus

Question 18

Bacteria that may have been the stimulus for an autoanti-Jkb

Answer 18

Proteus mirabilis