Kidney Stones Flashcards
(65 cards)
Functions of the kidneys:
Maintain fluid, electrolyte, and solute balance
Filtration of blood
Regulation of water homeostasis
Regulate blood pressure
Maintain acid-base balance
Hormone production
The kidneys secrete vasopressin also known as _____ which is stimulated by high osmolality.
ADH
Steps of the renin-angiotensin cascade system (3):
- Glomerulus secretes renin when blood volume decreases
- Renin stimulates the formation of angiotensin (vasoconstrictor)
- Angiotensin stimulates aldosterone to reabsorb sodium and fluid and also increases blood pressure
The kidney produces 2 important hormones:
Erythropoietin (EPO) and the active form of vitamin D
EPO stimulates what?
RBC production
T/F: Angiotensin is a vasodilator
False, vasoconstrictor
Nephrolithiasis are:
Kidney stones
Types of kidney stones
Calcium stones
Uric acid stones
Struvite stones
Cystine stones (rare)
Struvite stones ONLY form in the presence of _______, not very common.
Bacteria
Cystine kidney stones caused by a very rare genetic condition called ______.
Cystinuria, excess cystine excretion in urine
Kidney stone risk factors:
Male gender (it’s also increasing in women)
Family history/Genetics
Obesity
Oliguria (low urine excretion)
Hypercalciuria (high)
Hyperoxaluria (high)
Hyperuricosuria (high)
Hypocitraturia (low)
Urine pH
Types of calcium kidney stones (2):
Calcium oxalate (most common)
Calcium phosphate
T/F: Oliguria (low urine excretion) encourages kidney stones because it can lead to a concentration of substances accumulating in the urine that promote stone formation.
True
Hypocitraturia increases the risk of calcium oxalate stones because citric acid prevents _______ from binding to oxalate.
Calcium
Estrogen, particularly in premenopausal women, is thought to ________ urinary citrate levels, which helps prevent the formation of kidney stones. This is why post-menopausal women have an increased risk of kidney stones (hypocitraturia)
Increase
MNT for kidney stones
Monitor results 24hrs from collection
Fluid intake over 2.5 L/day to dilute solute concentration
Urine volume for kidney stones should exceed ___ L/day.
2
Cranberry juice helps treat _____ stones as it has anti-microbial properties.
Struvite
Citrus drinks helps prevent ______ stones from forming.
Calcium
Foods to limit/avoid for kidney stones:
Foods high in oxalates
Ca supplements in large doses
Vitamin C supplements in large doses
High sodium diets
High animal protein diets
Excessive fructose
Vitamin C in high doses can ______ risk of kidney stones.
Increase
T/F: Caffeine increases the risk of kidney stone since it increases Ca excretion.
F, it is a diuretic so it also promotes urine excretion
What increases uric acid excretion and increases the risk for uric acid stones (3)?
High animal protein diets
High purine foods
High fructose diets
Vitamin C in high doses increases _______ excretion in the urine, promoting calcium oxalate stones via hyperoxaluria.
Oxalate