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MAP II Midterm > Kidneys > Flashcards

Flashcards in Kidneys Deck (20):
1

Role of kidneys involved with blood flow?

- regulates BP by maintaining homeostasis of body fluid volume

2

An increase in extracellular fluid results in an increase of what?

blood volume and arterial pressure
--> kidneys excrete excess extracellular fluid to return BP to normal

3

Excess salt intake causes an increase in what?

MAP

4

_________ in blood volume --> ________ in blood pressure

increase; increase

5

Two determinants of long-term arterial pressure?

- location of renal output curve
- level of intake line

6

equation for arterial pressure?

CO x TPR

7

Direct effect of an increase in CO on arterial pressure?

increase in arterial pressure

8

What is the main determinant of extracellular fluid volume?

amount of salt accumulation in body

9

The effect of increase in sodium is _______ than effect of increase in H2O?

greater

10

What is it called if MAP > 110mmHg

Chronic hypertension

11

What is the first mechanism of controlling arterial pressure?

kidney

12

What is the 2nd mechanism of controlling arterial pressure?

renin-angiotensin

13

What hormone acts as an enzyme and is released when arterial pressure drops?

renin

14

Function of renin?

raises arterial pressure

15

Renin-angiotensin pathway?

decreased arterial pressure --> renin released from kidney --> renin acts on angiotensinogen --> forms angiotensin I --> transforms into angiotensin II --> retention of water/salt and vasoconstriction --> increase arterial pressure

16

What hormone is a powerful vasoconstrictor?

angiotensin II

17

2 effects of angiotensin? (effects that increase arterial pressure)

Direct - acts on kidneys to retain salt and water
Indirect - causes adrenal glands to secrete aldosterone which increases salt/water reabsorption by kidneys

18

salt regulation pathway?

increase in salt intake --> increase in extracellular volume --> increase in arterial pressure --> decrease in renin and angiotensin --> decrease in renal retention of salt and water --> return of extracellular volume to normal --> return of arterial pressure to normal

19

What is the cause of primary hypertension (silent killer)?

unknown cause

20

Weight gain and obesity role in hypertension?

- cardiac output increased
- SNS activity increased (SNS promotes renin)
- angiotensin II/aldosterone levels increased