KREB'S CYCLE Flashcards

1
Q

the central pathway of all metabolic processes

A

CITRIC ACID CYCLE

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2
Q

-sequence of reactions in the mitochondria that oxidizes the acetyl moiety of Acetyl-CoA to Carbon Dioxide

A

CITRIC ACID CYCLE

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3
Q

-reduces coenzymes that are reoxidized through the electron transport chain linked to the formation of ATP

A

CITRIC ACID CYCLE

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4
Q

the cycle start with the reaction between the acetyl moiety of Acetyl-CoA and the 4 Carbon dicarboxylic acid oxaloacetate, forming six-carbon tricarboxylic acid called

A

CITRATE

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5
Q

enzyme that catalyzes the reaction of oxaloacetate (4 carbon dicarboxylic acid) and Acetyl-CoA to form Citrate (6 carbon tricarboxylic acid)

A

Citrate Synthase

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6
Q

two sub-steps that occur during isomerization of citrate

A

DEHYDRATION, REHYDRATION

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7
Q

enzyme that catalyzes the isomerization of citrate

A

ACONITASE

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8
Q

H2O being a neutral compound is necessary to ________ of citrate forming it to Cis-Aconitate

A

RETAIN STABILITY

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9
Q

enzyme that catalyzes the dehydrogenation of isocitrate

A

ISOCITRATE DEHYDROGENASE

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10
Q

coenzymes involved in the dehydrogenation of isocitrate

A

MG or MN IONS

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11
Q

Isocitrate undergoes dehydration to initially form what

A

OXALOSUCCINATE

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12
Q

isocitrate undergoes decarboxylation to

A

a-ketoglutarate

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13
Q

enzyme involved in the oxidative decarboxylation of A-KETOGLUTARATE to form SUCCINYL-COA

A

A-KETOGLUTARATE DEHYDROGENASE

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14
Q

cofactors involved in the oxidative decarboxylation of A-KETOGLUTARATE to form SUCCINYL-COA

A

Thiamine Diphosphate, Lipoate, NAD+, FAD, and CoA

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15
Q

Succinyl-CoA is converted to

A

SUCCINATE

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16
Q

Succinyl-CoA is converted to succinate by the enzyme

A

SUCCINATE THIOKINASE OR SUCCINYL-COA SYNTHETASE

17
Q

the onwards metabolism of what is the same as in the reaction that occurs in the beta-oxidation of fatty acids

A

SUCCINATE

18
Q

enzyme involved in the conversion of SUCCINATE to FUMARATE

A

SUCCINATE DEHYDROGENASE

19
Q

enzyme involved in the conversion of FUMARATE to L-MALATE

A

FUMARASE

20
Q

fumarate to l-malate undergoes what reaction

A

rehydration reaction

21
Q

enzyme involved in the conversion of L-Malate to OXALOACETATE

A

MALATE DEHYDROGENASE