L1 Fungi

Question 1

hyphae

Answer 1

x

Question 2

mycelium

Answer 2

x

Question 3

rigid cell wall composition

Answer 3

x

Question 4

fungi cell membrane component

Answer 4

x

Question 5

chitin

Answer 5

structural part

Question 6

beta 1,3 glucan

Answer 6

sticking out

Question 7

amphotericin B

Answer 7

x

Question 8

Nystatin

Answer 8

x

Question 9

fungi environment requirement

Answer 9

x

Question 10

yeast reproduction method

Answer 10

budding

Question 11

pseudohyphae

Answer 11

long chains of cells…

Question 12

Yeast vs bacteria growth time

Answer 12

take longer

Question 13

Dimorphic fungi

Answer 13

37 deg - yeast, cold environment - mold

Question 14

“yeast in the ____, mold in the ____”

Answer 14

beast, cold

Question 15

Longitudinal extensions and produce spores

Answer 15

molds

Question 16

what proportion of fungi are linked to disease

Answer 16

300 vs 100,000 species

Question 17

mycoses

Answer 17

?

Question 18

labaratory diagnoses methods for fungi

Answer 18

x

Question 19

thermal dimorphism

Answer 19

37 deg - yeasts

25 - 30 deg - molds

Question 20

Fungi method of transmission/entry

Answer 20

spores - inhaled!

Question 21

Candida

Answer 21

ntibiotic therapy, catheters -> immunosuppressed conditons

Question 22

asperigillus

Answer 22

x

Question 23

main virulence factor

Answer 23

thermal dimorphism

Question 24

Most fungal treatments are _____

Answer 24

topical

Question 25

KOH mount

Answer 25

kills keratins and other cells to see only fungi in the plate

Question 26

PAS stain

Answer 26

x

Question 27

flucytosine

Answer 27

analogues nucleic acid...

Question 28

azoles

Answer 28

x

Question 29

Acid fast vs partial acid fast

Answer 29

x

Question 30

gluco..... and galato....

Answer 30

Antigen detection test

Question 31

other modes of fungal transmission

Answer 31

x

Question 32

organ most infected by fungi

Answer 32

x

Question 33

conidia

Answer 33

another name for fungal spore

Question 34

are fungi transmitted person to person?

Answer 34

nope, relax

Question 35

TB vs fungal infection

Answer 35

similar symptoms, normally will mention it is fungi

Question 36

clinical presentation of fungi

Answer 36

asymptomatic: x calcified granulomas ...

Question 37

culture for fungi

Answer 37

x

Question 38

characterisitc of blastomyces

Answer 38

thick cell wall!

Question 39

blasto.. usually located in

Answer 39

forest, decaying wood - no animals! ohio, river valley canada

Question 40

blasto.. uually infects

Answer 40

the lungs

Question 41

morphology of bastomyces

Answer 41

round yeast cells, budding

Question 42

cutaneous blato.. found in

Answer 42

people in contact w/ sil...

Question 43

immune system is adapted to do what to fungi?

Answer 43

inhibit transformation from mold to yeast

Question 44

whats special about the yeast form of fungi?

Answer 44

very resistant to killing - thick capsule

Question 45

the presenc eof yeats form indictes what in humans?

Answer 45

x

Question 46

pyrogranulmatous lesions

Answer 46

x

Question 47

calcofluor

Answer 47

stain...

Question 48

size of spore?

Answer 48

1 to 2 micrometer

Question 49

location of histoplasma

Answer 49

chicken coups, associated with bird and bat droppings... nitrogen rich soil! ohio river valley and mississipi

Question 50

histoplasma infection aka

Answer 50

ohio valley fever

Question 51

hisotplasma grows where?

Answer 51

intacellularly in macrophages

Question 52

histo.. important virulance factor?

Answer 52

mediate pH within phagolysosome

Question 53

histo.. staining

Answer 53

giemsa..

Question 54

Cocci... location

Answer 54

alkaline soil | semiarid hot climates - arizona

Question 55

cocci... structure

Answer 55

spherule form containing endospores

Question 56

arthroconidia

Answer 56

specific for cocci... in natural form

Question 57

cocci... structure in body

Answer 57

spherules (little yeast cell with endospores inside it)

Question 58

two forms of cocci...

Answer 58

soil - artoconidia | beast - spherules w/ endospores inside them

Question 59

disease characteristic of cocci..

Answer 59

abscesses

Question 60

test for cocci..

Answer 60

immunodiffusion test

Question 61

4 antifungals and function

Answer 61

x

Question 62

issue with taking antifungals orally

Answer 62

nephrotoxic

Question 63

often give ampho B w/ _______

Answer 63

flucytosine

Question 64

what do azoles inhibt?

Answer 64

x

Question 65

wht does c14 demethylase do?

Answer 65

x

Question 66

what does grisofulvin do and where does it inhibit fungi?

Answer 66

interfere w/ spindle formation - inhibit cell division | x

Question 67

where doe terbinafine act?

Answer 67

x