L2-10-E5 Flashcards
The nurse is caring for a patient who is being discharged home after a splenectomy. What information on immune function needs to be included in this patient’s discharge planning?
a. The mechanisms of the inflammatory response
b. Basic infection control techniques
c. The importance of wearing a face mask in public
d. Limiting contact with the general population
b. Basic infection control techniques
The spleen is one of the major organs of the immune system. Without the spleen, the patient is at higher risk for infection; so, the nurse must be sure that the patient understands basic principles of infection control. The patient with a splenectomy does not need to understand the mechanisms of inflammatory response. The patient with a splenectomy does not need to wear a face mask in public as long as the patient understands and maintains the basic principles of infection control. The patient who has had a splenectomy does not need to limit contact with the general population as long as the patient understands and maintains the basic principles of infection control.
An 18-month-old female patient is diagnosed with her fifth ear infection in the past 10 months. The physician notes that the child’s growth rate has decreased from the 60th percentile for height and weight to the 15th percentile over that same time period. The child has been treated for thrush consistently since the third ear infection. The nurse understands that the patient is at risk for which condition?
a. Primary immunodeficiency
b. Secondary immunodeficiency
c. Cancer
d. Autoimmunity
a. Primary immunodeficiency
Primary immunodeficiency is a risk for patients with two or more of the listed problems. Secondary immunodeficiency is induced by illness or treatment. Cancer is caused by abnormal cells that will trigger an immune response. Autoimmune diseases are caused by hyperimmunity.
The nurse is caring for a postoperative patient who had an open appendectomy. The nurse understands that this patient should have some erythema and edema at the incision site 12 to 24 hours post operation dependent on which condition?
a. His immune system is functioning properly.
b. He is properly vaccinated.
c. He has an infection.
d. The suppressor T-cells in his body are activated.
a. His immune system is functioning properly.
Tissue integrity is closely associated with immunity. Openings in the integumentary system allow for the entrance of pathogens. If the immune response is functioning optimally, the body responds to the insult to the tissue by protecting the area from invasion of microorganisms and pathogens with inflammation. Routine vaccinations have no bearing on the body’s response to intentional tissue impairment. The redness and swelling at the incision site in the first 12 to 24 hours is part of optimal immune functioning. A patient with erythema and edema that persist or worsen should be evaluated for infection. Suppressor T-cells help to control the immune response in the body.
While caring for a patient preparing for a kidney transplant, the nurse knows that the patient understands teaching on immunosuppression when she makes which statement?
a. “My body will treat the new kidney like my original kidney.”
b. “I will have to make sure that I avoid being around people.”
c. “The medications that I take will help prevent my body from attacking my new kidney.”
d. “My body will only have a problem with my new kidney if the donor is not directly related to me.”
c. “The medications that I take will help prevent my body from attacking my new kidney.”
Immunosuppressant therapy is initiated to inhibit optimal immune response. This is necessary in the case of transplantation, because the normal immune response would cause the body to recognize the new tissue as foreign and attack it. The body will identify the new kidney as foreign and will not treat it as the original kidney. While patients with transplants must be careful about exposure to others, especially those who are or might be ill, and practice adequate and consistent infection control techniques, they don’t have to avoid people or social interaction. The new kidney brings foreign cells regardless of relationship between donor and recipient.
The nurse is caring for a patient who was started on intravenous antibiotic therapy earlier in the shift. As the second dose is being infused, the patient reports feeling dizzy and having difficulty breathing and talking. The nurse notes that the patient’s respirations are 26 breaths/min with a weak pulse of 112 beats/min. The nurse suspects that the patient is experiencing which condition?
a. Suppressed immune response
b. Hyperimmune response
c. Allergic reaction
d. Anaphylactic reaction
d. Anaphylactic reaction
The patient is exhibiting signs and symptoms of an anaphylactic reaction to the medication. These signs and symptoms during administration of a medication do not correspond to a suppressed immune response but a type of hyperimmune response. While the patient is experiencing a hyperimmune response, the signs and symptoms allow for a more specific response. While the patient is experiencing an allergic reaction, the signs and symptoms presented in the scenario allow for a more specific response.
The nurse is preparing to administer medications to a patient with rheumatoid arthritis (RA). The nurse should explain which goal of treatment to the patient?
a. Eradicate the disease
b. Enhance immune response
c. Control inflammation
d. Manage pain
c. Control inflammation
Medications for RA are intended to control the inflammation that results from the body’s hyperimmune response. Autoimmune diseases like RA are chronic and currently have no curative treatments. Autoimmune diseases like RA are caused by hyperimmune response. The immune system needs to be suppressed, not enhanced. While the medications used for RA might help with pain management, the goal of medication intervention is to manage the inflammation.
The parents of a newborn question the nurse about the need for vaccinations: “Why does our baby need all those shots? He’s so small, and they have to cause him pain.” The nurse can explain to the parents that which of the following are true about vaccinations? (Select all that apply.)
a. Are only required for infants
b. Are part of primary prevention for system disorders
c. Prevent the child from getting childhood diseases
d. Help protect individuals and communities
e. Are risk free
f. Are recommended by the Centers for Disease Control and Prevention (CDC)
b. Are part of primary prevention for system disorders
d. Help protect individuals and communities
f. Are recommended by the Centers for Disease Control and Prevention (CDC)
Immunizations are considered part of primary prevention, help protect individuals from contracting specific diseases and from spreading them to the community at large, and are recommended by the CDC. Immunizations are recommended for people at various ages from infants to older adults. Vaccination does not guarantee that the recipient won’t get the disease, but it decreases the potential to contract the illness. No medication is risk free.
What instructions about plasmapheresis should the nurse include in the teaching plan for a patient diagnosed with systemic lupus erythematosus (SLE)?
a. Plasmapheresis eliminates eosinophils and basophils from blood.
b. Plasmapheresis decreases the damage to organs from T lymphocytes.
c. Plasmapheresis removes antibody-antigen complexes from circulation.
d. Plasmapheresis prevents foreign antibodies from damaging various body tissues.
c. Plasmapheresis removes antibody-antigen complexes from circulation.
Plasmapheresis is used in SLE to remove antibodies, antibody–antigen complexes, and complement from blood. T lymphocytes, foreign antibodies, eosinophils, and basophils do not directly contribute to the tissue damage in SLE.
The nurse should assess the patient undergoing plasmapheresis for which clinical manifestation?
a. Shortness of breath
b. High blood pressure
c. Transfusion reaction
d. Extremity numbness
d. Extremity numbness
Numbness and tingling may occur as the result of the hypocalcemia caused by the citrate used to prevent coagulation. The other clinical manifestations are not associated with plasmapheresis.
Which patient should the nurse assess first?
a. Patient with urticaria after receiving an IV antibiotic
b. Patient who is sneezing after subcutaneous immunotherapy
c. Patient who has graft-versus-host disease and severe diarrhea
d. Patient with multiple chemical sensitivities who has muscle stiffness
b. Patient who is sneezing after subcutaneous immunotherapy
Sneezing after subcutaneous immunotherapy may indicate impending anaphylaxis and assessment and emergency measures should be initiated. The other patients also have findings that need assessment and intervention by the nurse, but do not have evidence of life-threatening complications.
Ten days after receiving a bone marrow transplant, a patient develops a skin rash. What would the nurse suspect is the cause of the rash?
a. The donor T cells are attacking the patient’s skin cells.
b. The patient needs treatment to prevent hyperacute rejection.
c. The patient’s antibodies are rejecting the donor bone marrow.
d. The patient is experiencing a delayed hypersensitivity reaction.
a. The donor T cells are attacking the patient’s skin cells.
The patient’s history and symptoms indicate that the patient is experiencing graft-versus-host disease, in which the donated T cells attack the patient’s tissues. The history and symptoms are not consistent with rejection or delayed hypersensitivity.
A young adult female patient who is human immunodeficiency virus (HIV) positive has a new prescription for efavirenz (Sustiva). Which information is most important to include in the medication teaching plan?
a. Take this medication on an empty stomach.
b. Take this medication with a full glass of water.
c. You may have vivid and bizarre dreams as a side effect.
d. Continue to use contraception while taking this medication.
d. Continue to use contraception while taking this medication.
To prevent harm, it is most critical to inform patients that efavirenz can cause fetal anomalies and should not be used in patients who may be or may become pregnant. The other information is also accurate, but it does not directly prevent harm. The medication should be taken on an empty stomach with water and patients should be informed that many people who use the drug have reported vivid and sometimes bizarre dreams.
A patient who is human immunodeficiency virus (HIV)-infected has a CD4+ cell count of 400/μL. Which factor is most important for the nurse to determine before the initiation of antiretroviral therapy (ART) for this patient?
a. CD4+ cell count trajectory
b. HIV genotype and phenotype
c. Patient’s tolerance for potential medication side effects
d. Patient’s ability to follow a complex medication regimen
d. Patient’s ability to follow a complex medication regimen
Drug resistance develops quickly unless the patient takes ART medications on a strict, regular schedule. In addition, drug resistance endangers both the patient and community. The other information is also important to consider, but patients who are unable to manage and follow a complex drug treatment regimen should not be considered for ART.
The nurse will most likely prepare a medication teaching plan about antiretroviral therapy (ART) for which patient?
a. Patient who is currently HIV negative but has unprotected sex with multiple partners
b. Patient who was infected with HIV 15 years ago and now has a CD4+ count of 840/μL
c. HIV-positive patient with a CD4+ count of 160/μL who drinks a fifth of whiskey daily
d. Patient who tested positive for HIV 2 years ago and now has cytomegalovirus (CMV) retinitis
d. Patient who tested positive for HIV 2 years ago and now has cytomegalovirus (CMV) retinitis
CMV retinitis is an AIDS-defining illness and indicates that the patient is appropriate for ART even though the HIV infection period is relatively short. An HIV-negative patient would not be offered ART. A patient with a CD4+ count in the normal range would not typically be started on ART. A patient who drinks alcohol heavily would be unlikely to be able to manage the complex drug regimen and would not be appropriate for ART despite the low CD4+ count.
The nurse palpates enlarged cervical lymph nodes on a patient diagnosed with acute human immunodeficiency virus (HIV) infection. Which action would be appropriate for the nurse to take?
a. Instruct the patient to apply ice to the neck.
b. Explain to the patient that this is an expected finding.
c. Request that an antibiotic be prescribed for the patient.
d. Advise the patient that this indicates influenza infection.
b. Explain to the patient that this is an expected finding.
Persistent generalized lymphadenopathy is common in the early stages of HIV infection. No antibiotic is needed because the enlarged nodes are probably not caused by bacteria. Lymphadenopathy is common with acute HIV infection and is therefore not likely the flu. Ice will not decrease the swelling in persistent generalized lymphadenopathy
Which information about a patient population would be most useful to help the nurse plan for human immunodeficiency virus (HIV) testing needs?
a. Age
b. Lifestyle
c. Symptoms
d. Sexual orientation
a. Age
The current Centers for Disease Control and Prevention policy is to offer routine testing for HIV to all individuals age 13 to 64 years. Although lifestyle, symptoms, and sexual orientation may suggest increased risk for HIV infection, the goal is to test all individuals in this age range.
A patient who uses injectable illegal drugs asks the nurse about preventing acquired immunodeficiency syndrome (AIDS). Which response by the nurse is best?
a. “Clean drug injection equipment before each use.”
b. “Ask those who share equipment to be tested for HIV.”
c. “Consider participating in a needle-exchange program.”
d. “Avoid sexual intercourse when using injectable drugs.”
c. “Consider participating in a needle-exchange program.”
Participation in needle-exchange programs has been shown to decrease and control the rate of HIV infection. Cleaning drug equipment before use also reduces risk, but it might not be consistently practiced. HIV antibodies do not appear for several weeks to months after exposure, so testing drug users would not be very effective in reducing risk for HIV exposure. It is difficult to make appropriate decisions about sexual activity when under the influence of drugs.
Which nursing action will be most useful in assisting a college student to adhere to a newly prescribed antiretroviral therapy (ART) regimen?
a. Give the patient detailed information about possible medication side effects.
b. Remind the patient of the importance of taking the medications as scheduled.
c. Encourage the patient to join a support group for students who are HIV positive.
d. Check the patient’s class schedule to help decide when the drugs should be taken.
d. Check the patient’s class schedule to help decide when the drugs should be taken.
The best approach to improve adherence is to learn about important activities in the patient’s life and adjust the ART around those activities. The other actions are also useful, but they will not improve adherence as much as individualizing the ART to the patient’s schedule.
A patient with human immunodeficiency virus (HIV) infection has developed Mycobacterium avium complex infection. Which outcome would be appropriate for the nurse to include in the plan of care?
a. The patient will be free from injury.
b. The patient will receive immunizations.
c. The patient will have adequate oxygenation.
d. The patient will maintain intact perineal skin.
d. The patient will maintain intact perineal skin.
The major manifestation of M. avium infection is loose, watery stools, which would increase the risk for perineal skin breakdown. The other outcomes would be appropriate for other complications (e.g., pneumonia, dementia, influenza) associated with HIV infection.
A patient treated for human immunodeficiency virus (HIV) infection for 6 years has developed fat redistribution to the trunk with wasting of the arms, legs, and face. What recommendation will the nurse give to the patient?
a. Review foods that are higher in protein.
b. Teach about the benefits of daily exercise.
c. Discuss a change in antiretroviral therapy.
d. Talk about treatment with antifungal agents.
c. Discuss a change in antiretroviral therapy.
A frequent first intervention for metabolic disorders is a change in antiretroviral therapy (ART). Treatment with antifungal agents would not be appropriate because there is no indication of fungal infection. Changes in diet or exercise have not proven helpful for this problem.
The nurse prepares to administer the following medications to a hospitalized patient with human immunodeficiency (HIV). Which medication is most important to administer at the scheduled time?
a. Nystatin tablet
b. Oral acyclovir (Zovirax)
c. Oral saquinavir (Invirase)
d. Aerosolized pentamidine (NebuPent)
c. Oral saquinavir (Invirase)
It is important that antiretrovirals be taken at the prescribed time every day to avoid developing drug-resistant HIV. The other medications should also be given as close as possible to the correct time, but they are not as essential to receive at the same time every day.
To evaluate the effectiveness of antiretroviral therapy (ART), which laboratory test result will the nurse review?
a. Viral loading test
b. Enzyme immunoassay
c. Rapid HIV antibody testing
d. Immunofluorescence assay
a. Viral loading test
The effectiveness of ART is measured by the decrease in the amount of virus detectable in the blood. The other tests are used to detect HIV antibodies, which remain positive even with effective ART.
The nurse is caring for a patient who is human immunodeficiency virus (HIV) positive and taking antiretroviral therapy (ART). Which information is most important for the nurse to address when planning care?
a. The patient complains of feeling “constantly tired.”
b. The patient can’t explain the effects of indinavir (Crixivan).
c. The patient reports missing some doses of zidovudine (AZT).
d. The patient reports having no side effects from the medications.
c. The patient reports missing some doses of zidovudine (AZT).
Because missing doses of ART can lead to drug resistance, this patient statement indicates the need for interventions such as teaching or changes in the drug scheduling. Fatigue is a common side effect of ART. The nurse should discuss medication actions and side effects with the patient, but this is not as important as addressing the skipped doses of AZT.
Eight years after seroconversion, a human immunodeficiency virus (HIV)-infected patient has a CD4+ cell count of 800/μL and an undetectable viral load. What is the priority nursing intervention at this time?
a. Encourage adequate nutrition, exercise, and sleep.
b. Teach about the side effects of antiretroviral agents.
c. Explain opportunistic infections and antibiotic prophylaxis.
d. Monitor symptoms of acquired immunodeficiency syndrome (AIDS).
a. Encourage adequate nutrition, exercise, and sleep.
The CD4+ level for this patient is in the normal range, indicating that the patient is the stage of asymptomatic chronic infection when the body is able to produce enough CD4+ cells to maintain a normal CD4+ count. Maintaining healthy lifestyle behaviors is an important goal in this stage. AIDS and increased incidence of opportunistic infections typically develop when the CD4+ count is much lower than normal. Although the initiation of ART is highly individual, it would not be likely that a patient with a normal CD4+ level would receive ART.