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Neurosciences L > L2 Touch and Pain > Flashcards

L2 Touch and Pain Flashcards

(62 cards)

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1
Q

What is the sematosensory system?

A

a network of neurons that helps recognize objects, textures, and generate sensory-motor feedback

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2
Q

What types of receptors are mechanoreceptors?

A

Merkel cells
Meissner corpuscle
Ruffini corpuscle
Pacinian corpuscle
free nerve ending

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3
Q

What types of receptors are thermoreceptors?

A

Free nerve endings

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4
Q

What types of receptors are nociceptors?

A

Free nerve endings

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5
Q

All mechanoreceptors are A beta fiber types except which one? What fiber is it?

A

Free nerve endings ; C fibers

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6
Q

Warmth perceiving receptors are what type of fiber?

A

C

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7
Q

Cold perceiving receptors are what type of fiber?

A

A delta

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8
Q

What are merkel cells role in perception?

A

pressure, form, texture

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9
Q

What are meissner corpuscle’s role in perception?

A

motion,flutter

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10
Q

What are ruffini corpuscle’s role in perception?

A

stretch

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11
Q

What are pacinian corpuscle role in perception?

A

vibration

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12
Q

What are free nerve endings role in perception?

A

pressure

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13
Q

What are Adelta free nerve endings role in perception?

A

sharp localized pain

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14
Q

What are unmyelinated C free nerve endings role in perception?

A

burning

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15
Q

What are the two receptors in the superficial layer?

A

Meissner corpuscle
Merkel discs

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16
Q

What are the two receptors in the deep layer?

A

Ruffini corpuscle
Pacinian corpuscle

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17
Q

How do you measure receptive field?

A

two point discrimination

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18
Q

What is the relationship b/n receptive field size and ability to distinguish b/n sensations?

A

the smaller the receptive field, the more distinction ability

like in hands and face

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19
Q

How is cutaneous sensory transduced?

A

as membrane stretches, ion channels open

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20
Q

What are the rapidly adapting receptors?

A

Meissner’s corpuscle
Pacinian corpuscle

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21
Q

What are the slowly adapting receptors?

A

ruffini’s corpuscle
merkel disks

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22
Q

What is the reason for receptor adaption?

A

to allow for texture and pattern perception

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23
Q

How does somatosensory info enter the CNS?

A

vis dorsal root ganglia into dorsal root

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24
Q

What column does mechanosensory travel up in the spinal cord?

A

post./dorsal column

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25
What column does pain and temp. travel up in the spinal cord?
lateral column
26
Where does crossing over occur in the medial lemniscal system?
arcuate fibers in caudal medulla This is also known as the dorsal column
27
Mechanosensory receptors from the upper body travel up which tract?
cunate
28
Mechanosensory receptors from the lower body travel up which tract?
gracile
29
Where do mechanosensory receptors from the upper body synapse?
cunate nucleus
30
Where do mechanosensory receptors from the lower body synapse?
gracile nucleus
31
What sense is the Ventral post. lat. nucleus of the thalamus responsible for?
Sensory for body CHECK THIS (L)ateral Nucleus = (L)otion for the BODY
32
What sense is the Ventral post. med. nucleus of the thalamus responsible for?
sensory for the head/face (M)edial = (M)akeup for the FACE
33
T/F Different portions of the brain are dedicated to body parts based on density of info
True Example = the lips and hands have a lot of sensory density so they take a larger part of the brain than your torso.
34
VR-1 (TPVR-1) receptor is a receptor for what?
capsaicin
35
Where are VR-1 (TPVR-1) receptors found?
intracellularly
36
T/F there technically are pain receptors in the body?
False there are no pain receptors in the body
37
What Nociceptors respond to?
intense and possibly harmful stimuli
38
What type of pain are C fiber associated w?
dull, longer lasting pain
39
Where do Nociceptors cross over
anterior white commissure
40
What would be the effects of a left lower thoracic lesion?
reduced temp and pain sensation on right reduced two-point discrimination, vibration, and proprioception on left
41
What is lissauer's tract?
2-3 segments above and below the DREZ (dorsal root entry zone)
42
How is nociceptive perception maintained in case of injury?
lissauer's tract
43
What tract is assoc w/ pain reception
anterolateral (neospinothalamic)
44
Where are pain receptors synapsed at?
Ventral post lat nucleus of thalamus
45
Where does pain and temp info enter the spinal cord for upper body?
cervical spinal cord
46
Where does pain and temp info enter the spinal cord for lower body?
lumbar spinal cord
47
Where does pain and temp info enter the brainstem for the face?
midpons
48
Where does pain and temp info synapse for the face?
VPMN of thalamus
49
Ant. cingulate is the target for what?
avoidance/emotional component that drives behavioral responses
50
Amygdala is the target for what?
negative emotion
51
Hypothalamus is the target for what?
fight or flight
52
Superior colliculus is the target for what?
visually directs is to source of paine
53
Reticular formation is the target for what?
arousal to respond to pain
54
Periaqueductal gray is the target for what?
pain modulation
55
Where do spinotectal fiber synapse?
PAG
56
Where does the PAG project to?
Raphe nucleus Lateral tegmental nucleus
57
Where do the raphe nucleus and lateral tegmental nucleus synapse?
enkephalinergic interneurons
58
What is the role of the enkephalinergic interneurons?
release endogenous opioids to modulate pain like a negative feedback loop
59
perception of normally non-painful stimuli as being painful is called?
allodynia
60
Painful stimuli that is perceived to be more painful than expected is called?
hyperalgesia
61
What causes allodynia and hyperalgesia?
peripheral sensitization centra; sensitization
62
Release of neuropeptides from C fibers causes?
local sensitization

Neurosciences L (5 decks)

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