L26 Hypothalamus & Pituitary Gland Flashcards
Growth hormone releasing hormone from the hypothalamus (GHRH) acts on…
Somatotrophs in the anterior pituitary, which release growth hormone (somatotropin)
The hypothalamus plays a key role in…
Homeostasis
The pituitary gland is divided into two main parts, the…
Posterior and anterior
Together the hypothalamus and pituitary gland are known as the…
Hypothalamic-pituitary axis
The pituitary gland is also known as the…
Hypophysis
The hypothalamus connects to the pituitary glands via the…
Pituitary stalk
Hormones destined for the posterior pituitary gland are produced in the cell bodies of the neurons, which are actually located in the…
Hypothalamus
The hypothalamus releases…
Hypothalamic hypophysiotropic hormones into the portal circulation
The hypothalamic hypophysiotropic hormones (X-hormone releasing hormones) act upon the…
Anterior pituitary
Gonadotropin-releasing hormone (GnRH) acts on the…
Gonadotrophs to stimulate FSH and LH release
Growth-hormone releasing hormone (GHRH) acts on the…
Somatotrophs to stimulate GH release
Growth hormone is a…
Peptide hormone 191 AAs in length
Release of GH is inhibited by GH inhibiting hormone, aka…
Somatostatin
Acute metabolic actions of GH are… (4)
- Release of fatty acid from adipose tissue
- Diabetogenic, ‘anti-insulin’
- Increased gluconeogenesis in liver
- Increased production of insulin like growth factor 1 (IGF-1)
The long-term effects of GH are mediated via…
IGF-1
