L30 Muscle Tissue Flashcards
(26 cards)
Sphincters are operated by what type of muscle?
Skeletal muscle
What is being described:
Non-dividing cells surrounded by satellite cells and contained in a sarcolemma.
Muscle fibre
What are muscular satellite cells?
Undifferentiated muscle stem cells with regenerative potential.
Function as a reserve that can be activated to replace or increase muscle, as necessary.
When a satellite cell is activated by injury, what happens?
The satellite cell undergoes asymmetric division - forming one satellite cell and one myoblast. The myoblast matures and fuses to the muscle fibre.
True or false: Skeletal muscle is striated
True
True or false: Skeletal muscle is controlled by the autonomic nervous system
False, it requires somatic or voluntary input.
Fused myocytes form a __1__, and are surrounded by endomysium.
Bundles of 1 form muscle fascicle, surrounded by __2__.
Bundles of 2 form muscle, surrounded by __3__.
1) muscle fibre
2) perimysium
3) epimysium
What are the myofilaments inside a muscle fibre?
Thin: actin, tropomyosin, troponin
Thick: myosin
What is a myofibril?
Any one of the contractile threads found in a muscle fibre.
What are transverse tubules (T-tubules) and what do they do?
‘Tunnels’ throughout muscle fibres that conduct action potentials from the sarcolemma to initiate contraction.
What is a sarcomere?
The smallest functional unit of muscle (not the smallest structural unit).
Contraction happens here.
What forms the I band of the sarcomere?
Thin bands of actin
It looks lighter because actin is isotropic
What forms the A bands of the sarcomere?
Thick bands of myosin
Anisotropic, therefore appears dark
What is the Z line in the sarcomere?
Protein chain that supports the actin filaments (I bands).
Z = zig zag
What is the M line in a sarcomere?
Consists of proteins supporting the thick myosin filaments
Where is the H zone on a sarcomere?
The central region that contains only thick filaments
How is contraction achieved in the sarcomere?
Sliding of thick and thin filaments in the zone of overlap.
True or false: Striations can be found in cardiac muscle
True
Is cardiac muscle mononucleated or multinucleated?
Mononucleated. Cells are not fused.
Is skeletal muscle mononucleated or multinucleated?
Multinucleated.
Myoblasts fuse together to form multinucleated fibres
Cardiac muscle contains intercalated discs at the ends of the cardiocytes. What structures are found here and why?
Gap junctions and desmosomes allow exchange of ions and molecules - allows spread of action potentials.
True or false: A sarcomere Z line appears zig zag shaped, and the M line appears straight
True
z line = zig zag
True or false: cardiac muscle contraction is not reliant on the nervous system for stimulation.
True
Pacemaker cells stimulate contractions; the nervous system can only alter the rate of activity.
True or false: Smooth muscle is incapable of regeneration
False.
Smooth muscle cells can divide, therefore the tissue is capable of regeneration.