L6-respiratory physiology and lung volumes Flashcards

1
Q

what happens due to the turbulence in the upper respiratory tract?

A

turbulence in the upper respiratory tract and large surface allow inhaled particles to beome trapped in the mucus lining in the mucosa

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2
Q

what happens to smaller particles

A

these are trapped by the mucus further down by branching respiratory tract

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3
Q

what do the macrophages intake respiratory tract do?

A

help clear any particles that may reach the alveoli

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4
Q

what implications does filtration have?

A

implications for drug delivery

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5
Q

what do the cillia of the mucosa do?

A

beat in a rythmic and coordinated way and carry trapped particles towards the pharynx and the digestive tract

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6
Q

what happens in the digestive tract

A

swallowed particles are then broken down by a combination of the low pH in the stomach and pepsin

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7
Q

what is special about the tonsils and adenoids

A

they are rich in lymphatic tissue

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8
Q

what is the immunological response?

A

fixed and wondering macrophages ingest particles and function as antigen presenting cells so activate the immune system

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9
Q

what are some signs and symptoms of respiratory disease

A

cough, sneeze, difficulty in breathing (dyspnoea), cyanosis

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10
Q

what is a cough

A

reflex response that helps to clear congestion in the lower respiratory tract. a common sign of respiratory disorder

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11
Q

what does a cough involve

A

inspiration

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12
Q

how is a cough produced

A

closure of epiglottis and vocal cords
forceful contraction of abdominal muscles
opening of glottis and vocal cords
expulsion of air under pressure

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13
Q

at what speed is air expelled during a cough

A

75-100km/h

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14
Q

what causes a cough

A

irritation of lower respiratory tract

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15
Q

what is dyspnoea

A

difficult or laboured breathing- shortness of breath (air hunger)

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16
Q

what can cause dysponea

A

can be caused by reduced lung compliance

17
Q

what can dysponea be a result of

A

airway obstruction

18
Q

what is cyanosis

A

blueness of the skin associated with low blood PO2 in the capillary beds

19
Q

what happens during peripheral cyanosis

A

most peripheral cyanosis caused by peripheral vasoconstriction- often seen as a response to extreme cold

20
Q

what can cause cyanosis

A

can be caused by respiratory disorders resulting in blood supply exceeding ventilation rate

21
Q

what is meant by blood supply exceeding ventilation rate

A

increased concentration of reduced haemoglobin, thus an increased physiological shunt