L62. Blood Flashcards

(35 cards)

1
Q

What are erythrocytes?

A

Red blood cells

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2
Q

What are leucocytes?

A

White blood cells

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3
Q

What are thrombocytes?

A

Platelets

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4
Q

Name 4 substances present in the plasma.

A

ECF, water, glucose, plasma proteins

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5
Q

Name 3 plasma proteins.

A

Albumins
Globulins
Fibrinogen

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6
Q

What does blood volume depend on?

A

A person’s size

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7
Q

Give rough blood volumes for men and women.

A

Men - 70ml/kg

Women - 60ml/kg

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8
Q

Give the size of a red blood cell (diameter).

A

6-8 um.

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9
Q

What is the shape of a red blood cell?

A

Concave disk

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10
Q

Where are red blood cells formed?

A

Bone marrow

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11
Q

Give the lifespan of a red blood cell.

A

120 days

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12
Q

What is erythropoiesis?

A

production of red blood cells.

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13
Q

What 2 substances does erythropoiesis require?

A

Folic acid

Iron

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14
Q

Describe the structure of haemoglobin.

A

Globular protein
2 alpha and 2 beta proteins chains
4 heam groups
Iron reversibly binds

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15
Q

Name 3 granulocytes.

A

neutrophils
basophils
eosinophils

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16
Q

Name 2 agranulocytes

A

monocytes

lymphocytes

17
Q

What are neutrophils involved in?

A

Acute inflammation
phagocytic
non-specific

18
Q

What are basophils involved in?

A

They produce histamine

19
Q

What are eosinophils involved in?

A

allergic reactions

20
Q

What are monocytes involved in?

A

Antigen presenting

become macrophages

21
Q

What are lymphocytes involved in?

A

cell mediated immunity (T) and humoral immunity (antibody-producing B cells)

22
Q

What are platelets derived from?

A

Megakaryocytes

23
Q

Describe how blood groups are determined.

A

Erythrocytes carry antigens on their membranes with determine blood groups.
AB antigens
Rhesus antigen (Rh)

24
Q

Which antigen does “Blood group A” carry?

25
Which antigen does "Blood group B" carry?
B
26
Which antigen does "Blood group AB" carry?
AB
27
Which antigen does "Blood group O" carry?
-
28
Which antibodies does "Blood group A" carry?
Anti-B
29
Which antibodies does "Blood group B" carry?
Anti-A
30
Which antibodies does "Blood group AB" carry?
-
31
Which antibodies does "Blood group O" carry?
Anti-A and Anti-B
32
Which blood type is the universal recipient?
AB
33
Which blood type is the universal donor?
O
34
What happens if a Rh- person receives Rh+ blood?
Nothing major | They develop anti-Rh antibodies.
35
What happens if a Rh- mother has an Rh+ baby?
If the mother gets some Rh+ blood in her, she will develop anti-Rh antibodies. If she has another Rh+ baby, they will attack the baby's red blood cells causing haemolytic disease in the baby.