last exam presentations.powerpoint Flashcards

1
Q

smoking increase risk of

A
1st trimester miscarriage
ectopic 
low birth weight
placenta previa/abruption 
fetal growth restriction 
preterm birth/labor 
SIDS 
chronic asthma in children
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2
Q

Is quitting smoking by the end of the first trimester….

A

reverse the adverse effects on the fetus

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3
Q

5 A’s approach smoking cessation

A
Ask about tobacco use
advise to quite
assess willingness to make an effort to quit
assist attempt to quit
arrange follow up
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4
Q

what is the first line of treatment (smoking) in pregnant women

A

behavioral

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5
Q

when does pharmacotherapy recommended for pregnant women

A

those who smoke more than 1 pack / day

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6
Q

Is woman is more likely to quit smoking during pregnancy than any other time in her life

A

yes

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7
Q

Nicorette

A

MOA:cholinergic-receptor agonist that replaces nicotine to reduce withdrawal symptoms
S/E- indigestion, nausea, hiccups traumatic injury to oral mucosa and/or teeth, irritation and/or tingling of the tongue, mouth, and throat, oral mucosal ulceration, jaw-muscle ache, eructation, gum sticking to teeth, unpleasant taste, dizziness, lightheadedness, headache, insomnia
Contraindications: known allergy to nicotine or methol, patients with TMJ
Prescription: Nicorette Gum 2mg pieces, chew 1 piece gum prn nicotine cravings. not to exceed 9 pieces daily.

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8
Q

what amount of Alcohol is approved during pregnancy

A

NO AMOUNT is allow

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9
Q

Alcohol uses increase risk of

A
miscarriage
stillborn
developmental delay
preterm birth
physical delay
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10
Q

what decrease alcohol comsumption

A

assessment of alcohol

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11
Q

T-ACE screening tool

A

How many drinks does it take to feel high? (TOLERANCE)
Have ppl ANNOYED you by criticizing your drinking?
Have you ever felt that you needed to CUT DOWN on your drinking?
Have you ever had a drink first thing in the morning to steady your nerves or get ride of hang over (EYE OPENER)

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12
Q

What are the criteria to dx Fetal Alcohol Syndrome

A

3 facial features:
smooth ridge between the nose and upper lip (smooth philtrum)
Thin upper lip
short distance between the inner and outer corners of the eyes, giving the eyes an wide-spaced appearance
Growth deficits
CNS problems

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13
Q

Cyanocobalamin (Vitamin B12)

A

MOA: coenzyme for various metabolic functions, including fat and carbs metabolism and protein synthesis, used in cell replication and hematopoiesis
S/E: dizziness, headache, nervous, and excitable, upset stomach or throwing up, loose stools (diarrhea)
contraindications: hypersensitivity to cyanocobalamin, cobalt, or any component of the formulation
Prescription: 1mL (1000mcg) IM daily for 7 days, then inject 1mL monthly

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14
Q

Physical Abuse Facts

A

men are 5 times more likely than women to be the abuser in a relationship
men use abuse as form of coercion or control, while women often use it in self defense
studies show that younger women (20 y.o and younger) are more at risk of domestic violence)
pregnant women suffering from domestic abuse more likely to abuse drugs, alcohol, and tobacco. Depression and anxiety are commonly seen in pregnant women experiencing domestic abuse
pregnant women suffering from domestic violence more likely to get late or no prenatal care d/t their partner’s controlling behavior
providers much educate all women and domestic abuse does occur, the detrimental physical and emotional consequences, and where to get help if they are being abused now or in the future.

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15
Q

Cocaine

A

coke blow or crack can be snorted, injected or smoked

slow metabolism of drug in fetal blood stream causes prolonged fetal exposure

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16
Q

Cocaine increases risk of

A

miscarriage

placental abruption

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17
Q

how does Cocaine easily crosses the placenta

A

simple diffusion

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18
Q

Fetal/neonatal problem with Cocaine uses

A
PTB
LBW
respiratory distress
bowel and cerebral infarctions
FGR 
seizures 
**long-term effects may not be seen for years and includes cognitive behavioral and learning disorders.
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19
Q

Buspirone (Buspar)

A

anti-anxiety agent
buspar has a attraction to serotonin 5 HT & dopamine receptors
off label: antidepressant
side effects: dizziness, fatigue, anxiety, headache, or dyspepsia
contraindications: renal or hepatic disease, breastfeeding.
Pregnancy cat. B

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20
Q

sexual abuse

A

a person is sexually abused when one person engages another person in any action which the perpetrator anticipates will be sexually stimulating. this can include intercourse, touching, exposure of genital organs, showing pornographic material or talking about sexual thing in an erotic ways.

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21
Q

incidence of sexual abuse

A

18-25% before age of 16

all socio economic and educational background

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22
Q

how sexual abuse affects women’s life

A
all relationship
how she handles hardships, 
daily difficulties
children and friends
how she take care of neglets her own health and how she feels about herself. many women of sexual abuse turn to abusive substance use or behaviors include suiide ideation in order to cope with situation or memories.
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23
Q

how sexual abuse effect pregnancy

A

pregnancy can trigger for feelings of alarm and humiliation. flashbacks and anxiety attacks are common during vaginal exams and labor and delivery. women of sexual abuse may experience intense somatic and psychosocial reaction to labor and delivery.

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24
Q

how women’s response to sexual abuse

A

guilt
responsible for abuse
do not report d/t fear of being judged or blamed
fear of repercussions from perpetrator
fear of changes this may bring to their lives.
most victims wish they could tell someone what has happened to them, but the need to be asked straightforward

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25
midwifery care for sexual abuse women
** screen all women ** help identify trigger that may cause distress ** allow the women to feel control during exam labor birth ** allow her to dissociate in order to allow exams and labor to continue midwife needs to allow the woman to handle her exams and labor in a way will most helpful to her build trust and show non-judgement with the client so that she can plan the best approach to her pregnancy labor birth be patient give time to make decisi0n know your state & local law about mandatory reporting document all conversation. she should not have to repeat her story anticipate emotional difficulty after baby is born
26
SAVER
(S)creen all women (A)Ssist in acknowledging her story and help her wok through emotional resonse. (V)alidate her by believing and not judging her (E)valuate for current safety and suicide risk (R)efer to specialist.
27
Heroin
synthetic opioid that is injected snorted or smoke
28
complications associated with heroin
malnutrition sexually transmitted infections and infectious diseases during and outside pregnancy heroin is also associated with preeclampsia and placental abruption as well as intrauterine fetal death, fetal growth restriction and prematurity
29
fetal effects on heroin use
withdrawal symptoms may be life-threatening risk of developmental delay and behavioral problems increase of SIDS
30
IV drug use is associated with increase in ....
HIV and hepatitis which may be transmitted before or during birth
31
methadone treatment
standard care in pregnancy that allows pregnant women to discontinue using heroin while mitigating withdrawal symptoms.
32
methadone
MOA: inhibits ascending patin pathways by binding to CNS opiate receptors change perception response to pain
33
indications for methadone
management of moderate to severe pain standard of care in pregnant women with opiate additction Pregnancy cat. C
34
methadone side effects
arrhythmia cardiac arrest hypotension sedation/disorientation, dizziness, physical psychological dependence rash abdominal pain, nausea anorexia biliary tract spasm constipation urinary retention or hesitancy weakness pulmonary edema respiratory depression or arrest
35
contraindications for methadone
hypersensitivity respiratory depression paralytic ileus simultaneous selegine
36
special consideration for methadone
regulation on dispensation vary by state may require referrals to substance abuse and mental health specialist exception: inpatient admission for condition other than opiod addiction short course <3 days while appropriate care is secured opioid withdrawal syndrome in neonate may be fatal
37
substance abuse risk factors
``` late to prenatal care hx. miscarriage, preterm birth poverty infection decrease fetal movement smoker multiple partners poor dental health low BP increase BP ```
38
thrombophlebitis
inflammation of a vein caused by a blood clot (thrombosis)
39
superficial thrombophlebitis
localized heat, pain, or tenderness, inflammation, palpable knot
40
Deep thrombophlebitis
unilateral edema, generalize warmth and redness, mild tachycardia, abrupt onset, severe leg pain, worsening with motion or standing, pain with calf pressure.
41
risk for venous thrombosis and embolism
4-6 times higher during pregnancy pregnancy= hypercoagulability in pregnancy venous thrombosis is often in the deep veins of the lower extremities (usually the left leg) ``` cesarean delivery diabetes hemorrhage immobility multiparity multifetal preeclampsia over 35 y.o dehydration smoking obesity ```
42
Virchow's triad
stasis hypercoagulate state vascular trauma
43
pulmonary embolism
25% of untreated venous thrombosis in pregnancy thrombosis r/t pulmonary embolism often originates in the iliac veins anticoagulation decreases risk of pulmonary embolism to less than 5% pulmonary embolism cause 10% of maternal death.
44
low molecular weight heparin
enoxaparin aka lovenox MOA: anticoagulant : inhibits formation of blood clots. DVT prophylaxis & treatment S/E: bleeding, nausea, diarrhea, thrombocytopenia, anemia, bruising, increase AST/ALT, irritation at injection site, fever
45
contraindication for heparin
sensitivity to enoxaparin pork products benzyl alcohol (in multiple dose vials, thrombocytopenia associated with a positive in vitro test for antiplatelet antibodies in the presence of enoxaparin, active major bleeding
46
what is compression ultrasound
gold standard for rule out DVT
47
hypothyroidism
second most common endocrine disease that affects women of reproductive age. characterized by increase TSH decrease T4 levels
48
maternal risk of untreated hypothyroidsm
``` anemia miscarriage preeclampsia gestational hypertension abruption and postpartum hemorrhage ```
49
fetal risk of untreated hypothyroidism
fetal loss preterm birth low birth weight potential cognitive delays postnatal
50
Labs draws for hypothyroidism
every 4 weeks until the second half of pregnancy and then at least once in the third trimester it typically takes 4 weeks for the thyroxine medication to impact the TSH levels, thus the rationale for lab draws every 4 weeks
51
Fetus effect by hypothyroidism mom
the fetus is completely dependent on the mom first 10-12 weeks of pregnancy for the thyroid hormone. after the first trimester the fetus's thyroid will begin making the thyroid hormone on its own.
52
Levothyroxine (Synthroid, Eltroxin)
MOA: thyroid hormone replacement S/E: signs of allergic rx hives itching rash swelling of face, wheezing tight chest heartbeat that doesn't feel normal chest pain hair loss in the first few months Contraindications: hypersensitivity to levothyroxine thyrotoxicosis, adrenal insufficiency that is uncorrected
53
Appendicitis
common non-obstetric indication for surgery during pregnancy
54
what does Appendicitis mimic
constipation, morning sickness preterm labor placental abruption
55
dx appendicitis | Rovsing's sign
pain in RLQ when deep pressure is applied then withdrawn in LLQ
56
Psoas signs (appendicitis)
client raises right thigh against counter pressure of CNM's hand on knee
57
Obturator sign (appendicitis)
internal rotation of right leg with flexion of knee and hip
58
why pregnancy can delay diagnosis appendicitis
appendix location has shifted d/t growing uterus difficulty to visualizing via U/S N/V frequently associated with normal pregnancy some leukocytosis is common in normal pregnancy
59
ruptured appendix is more common in which trimester
8% in 1st 12% in 2nd 20% in 3rd
60
Morphine Sulfate
to relieve severe acute pain or moderate to severe, chronic pain it is also used as a supplement to anesthesia parenerally and for analgesia during labor MOA: depresses pain impulse transmission at the spinal cord level by interacting with opioid receptors to effectively relieve pain w/o producing loss of consciousness
61
Side effects of MOrphine sulfate
REspiratory depression, respiratory arrest, apnea, thrombocytopenia, flushing, rash, pruritus, dizziness , visual disturbances, euphoria, mental clouding or depression, N/V, constipation, cardiac arrest, tachycardia, MI , Urinary retention, oligura, bradycardia, palpations.
62
contraindications of morphine sulfate
``` hypersensitivity addiction (opioid) hemorrhage bronchial asthma increased intracranial pressure pregnancy cat. C ```
63
Rhesus Factor Antigen
there are five RBC Rhesus factor antigens: C, c, D, E, and e; BIG "D" is the most common and the most immunogenic of them all
64
D-antigen
present of D-antigen means you have a "positive" blood type
65
racial origins for D-antigens
``` Native American Inuits Asian are 99% positive African Americans are 93% D-positive Caucasians are 87% D-positive ```
66
what are the major concern with isoimmunization
erythroblastosis fetalis in future pregnancies this occurs when the maternal immune system develops anti-D antibodies which can across the placenta and lyse the fetal RBC
67
why Isoimmunization is quite rare
low prevalance of incompatible RBC antigens variable immune response to antigen by mother insufficient transplacental passage of maternal antibodies or fetal antigens variable antigenicity
68
Rho(D) immune Globulin (Rhogam)
MOA: suppresses immune response and antibody formation by Rh negative individuals to Rh positive RBCs thereby preventing isoimmunization
69
Side effects of Rh(D) Immune Globulin (Rhogam)
discomfort, pain, swelling or redness at the injection site, hyper/hypotension, pallor, vasodilation, chills, dizziness, fever, HA, malaise, somnolence, abdominal pain, diarrhea, nausea, vomiting, back pain, myalgia, weakness, , anaphylaxis, diaphoresis, shivering rash or pruritis doses: 300mcg IM
70
Tuberculosis
latent phase- asymptomatic Active phase symptoms: chronic cough, blood tinged sputum, night sweat, wt loss, fever weakness, chest pain, shortness of breath
71
high risk employment area (TB)
``` hospitals homeless shelters correctional facilities nursing home drug rehabilitation centers. ```
72
diagnostic testing for TB
``` chest Xray gram stain & culture of sputum CBC baseline liver and renal function hepatitis panel ```
73
PPD interpretation | 5mm
HIV infections, close contact with newly dx active scars on chest x-rays suggest prior active infection, organ transplant recipients, immunosuppressed
74
PPD interpretation | 10mm
immigrants from areas with high TB prevalence, low-income/medically underserved IV drug users, resident and employees of high risk facilities, lab personnel, chronic illness, infants, young children
75
PPD interpretation: | 15mm
no known risk factors.
76
Medications for treatment of TB
INH Rifampin Rifampin with Pyrazinamide Recommend B6 supplements with drug therapy
77
Isoniazid (INH)
use for latent and active TB | 5mg/kg daily for 6-9 months (dependent upon chest radiograph)
78
side effect of Isoniazid (INH)
``` flushing rash hypertension tachycardia dizziness memory impairment slurred speech n/v hyperglycemia hepatic enzyme elevation hepatitis peripheral neuropathy mild CNS effects ``` take 1 hour before and 2 hours after eating (empty stomach) Pregnancy cat C small amounts excreted in breastmilk, but breastfeeding is not contracindicated
79
Liver function test
monthly while on INH
80
Risk of hepatitis
increase with age and alcohol use
81
vitamin B6 (pyridoxine)
prevent peripheral neuropathy and CNS effects while taking INH
82
Depression & pregnancy
one of the common disorders that occur in pregnancy pregnancy is believed to change brain chemistry, due to hormonal changes, possibly causing triggers for more severe depression
83
why depression are undertreated
due to hesitancy from patients and providers, the majority of patients diagnosed with depression are either not treated at all or undertreated.
84
SSRI is associated wit what
pulmonary HTN in the newborn and preterm labor
85
untreated depression in pregnancy was been related to what kind of perinatal complications
substance abuse miscarriage preeclampsia and low birth weight
86
what are the first line treatment for depression in pregnancy and lactation
SSRI | though Paxil is category D medication.
87
Anxiety
no valid screening tool for anxiety in pregnancy poor screening and poor disclosure by patients = increased morbidity and mortality 85% of all depressed women have one or more anxiety disorder Perinatal anxiety increases with life stress r/t pregnancy and postpartum
88
s/sx of anxiety
anxiousness, fatigue, fluctuation in mood, these are often seen as normal in pregnancy and there fore are not reported until debilitating
89
4 types of anxiety
GAD PTSD OCD panic disorder
90
treatment in pregnancy
SSRI then SNRI | TCA and lastly benzos
91
first line drug for anxiety
Zoloft | MOA : antidepressant with selective inhibitory effects a presynaptic serotonin (5HT) reuptake and only very
92
sx/s zoloft
s/x
93
Bariatric surgery
pregnant patients with hx of bariatric surgery are at risk of calcium, iron, and fat soluble vitamin deficiencies ***best to wait 1-2 years after surgery to conceive
94
what are the risks of being pregnant post surgery (and at a healthy weight)
are lower than the risk of being obese and pregnant !!! so lose weight before getting pregnant :o)
95
what to confirm healthy fetal growth for post bariatric surgery
serial U/S to confirm
96
ABO incompatibility
ABO incompatibility is the most common cause of hemolytic anemia in newborns it most commonly occurs with maternal blood type 0 and new born blood type A. Mothers with an O blood type already have anti-A and anti-B antibodies, even prior to their first pregnancy. Exposure to fetal blood of a different blood type can initiate and immune response. Most of these antibodies do not across the placenta but some can remain in fetal blood after delivery. This is why the effects are seen after the baby is born.
97
ABO incompatibility vs Rh isoimmunization
frequently seen in first born babies (ABO incompatibility) | ABO incompatibility rarely become more severe with each pregnancy
98
tests and treatment of ABO incompatibility
There are no prenatal tests for ABT incompatibilty management includes testing cord blood for neonatal blood type, direct coombs testing, and monitoring for neonatal hyperbilirubinemia.
99
Asthma
up to 8% pregnant women in U.S are asthmatic and this number may be increasing Pregnant women's lungs have less functional residual capacity so are more susceptible to the potential hypoxia caused by asthma's inflamation
100
Pregnancy and asthma
more severe or uncontrolled the asthma is prior to conception, the more likdly the woman is to have an exacebation during pregnancy There is a slightly increased risk of preterm labor and pre-eclampsia, with severe disease and poor control increasing these risks
101
respiratory alkalosis & asthma
severe asthma affect mom's oxygenation, the fetus may be affected (ie hypoxemia or fetal growth restriction) women should continue their current medication regimen throughout pregnancy because of the risk of worsening symptoms outweights any potential risk (no direct link between asthma medications and fetal anomalies has been found)