Learning And Memory (1-20) Flashcards

(35 cards)

1
Q

What is the definition of learning?

A

Modification in behaviour due to increase in knowledge or skills

Involves acquiring new information and experiences

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2
Q

What is memory?

A

Ability to retain and recall information and experiences

Allows learned behaviour to persist over time so it can guide future behaviour

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3
Q

What type of memory is declarative (explicit) memory?

A

Systems-level memory that can be consciously recalled or verbalised

Includes facts and events

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4
Q

What did Lashley’s research in the 1920s-30s conclude about memory?

A

Memory is NOT localised to a single cortical region; it is distributed across the cortex

More cortex removed = worse memory, regardless of location

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5
Q

What was the conclusion of Penfield’s stimulation of the temporal lobes?

A

Temporal lobe plays a role in storing episodic memories

Some patients reported vivid recollections of past events

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6
Q

What was the outcome of Henry Molaison’s surgery?

A

Developed profound anterograde amnesia; could NOT form new long-term declarative memories

Procedural memory remained intact

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7
Q

What are the two main subtypes of declarative memory?

A
  • Episodic memory
  • Semantic memory
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8
Q

Define episodic memory.

A

Memory for specific events or experiences, tied to time and place

Involves mental time travel

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9
Q

Provide an example of episodic memory.

A

Remembering the first day at university

Involves recalling specific personal experiences

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10
Q

Define semantic memory.

A

General knowledge about the world, not personal but factual

Example: Knowing Paris is the capital of France

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11
Q

What is procedural memory?

A

Non-verbal, unconscious memory for skills and habits

Example: Knowing how to ride a bike

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12
Q

What brain areas are involved in procedural memory?

A
  • Basal ganglia
  • Cerebellum
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13
Q

Which brain regions are involved in long-term semantic and episodic memory?

A

Cerebral cortex, particularly temporal and frontal lobes

Also includes basal ganglia and limbic system

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14
Q

What role does the hippocampus play in memory?

A

Central for declarative memory, especially forming new long-term episodic memories

Part of the limbic system

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15
Q

What did Maguire et al.’s 1997 study on taxi drivers demonstrate?

A

Experience-dependent plasticity in the human hippocampus

Increased volume of posterior right hippocampus correlated with time spent as a taxi driver

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16
Q

What is the process of memory storage from short-term to long-term?

A

New info enters short-term memory, without rehearsal it is forgotten, with repetition it is encoded into long-term memory

Long-term retrieval is slower but stable

17
Q

What is Hebb’s Rule?

A

Neurones that fire together, wire together

Repeated activation strengthens synapses

18
Q

What is synaptic plasticity?

A

The basis of Long-Term Potentiation (LTP), where repeated activation strengthens connections between neurones

Underlies the mechanisms of memory

19
Q

True or False: Inactive synapses are strengthened.

A

False

Inactive synapses are weakened or eliminated

20
Q

What does the model of Hebbian plasticity explain?

A

How practice leads to memory and how neural networks are shaped by repeated activity

Active axons stabilise synapses

21
Q

What organism did Eric Kandel study to explore synaptic plasticity?

A

Aplysia, a sea slug with a simple and well-mapped nervous system.

Kandel’s work focused on the gill withdrawal reflex in Aplysia.

22
Q

What is sensitisation in the context of Aplysia’s learning?

A

Stronger gill withdrawal response after repeated shocks.

This indicates non-associative learning leading to synaptic growth.

23
Q

What is the conclusion from Kandel’s work on Aplysia?

A

Non-associative learning can lead to synaptic growth and neuroplasticity.

Kandel won the Nobel Prize in 2000 for this foundational work.

24
Q

What does the gill withdrawal reflex circuit diagram track?

A

Behavioral and synaptic change in Aplysia.

It shows the effects of single vs. repeated shocks on memory.

25
What is Long-Term Potentiation (LTP)?
A long-lasting increase in synaptic strength after high-frequency stimulation. ## Footnote LTP is especially seen in the hippocampus (CA3 → CA1 pathway).
26
Which neurotransmitter is primarily involved in LTP?
Glutamate. ## Footnote LTP requires NMDA and AMPA receptors for its mechanism.
27
What role does calcium (Ca²⁺) play in memory formation?
Triggers signalling cascades that strengthen the synapse. ## Footnote Ca²⁺ influx through NMDA is crucial for LTP.
28
What is Long-Term Depression (LTD)?
A long-lasting decrease in synaptic strength after low-frequency stimulation. ## Footnote LTD is often observed in the cerebellum and results in synaptic weakening.
29
How does LTP differ from LTD in terms of stimulation and effect?
LTP requires high-frequency stimulation and leads to strengthening, while LTD involves low-frequency stimulation and results in weakening. ## Footnote LTP and LTD are mechanisms of synaptic plasticity.
30
Define memory consolidation.
Stabilising a memory after it’s first acquired. ## Footnote It requires new protein synthesis for long-term memory retention.
31
What is sensitisation?
Stronger response to a stimulus after repeated exposure. ## Footnote This is a form of non-associative learning.
32
What is synaptic plasticity?
The ability of synapses to strengthen or weaken over time. ## Footnote It is crucial for learning and memory processes.
33
What are the receptors involved in LTP?
NMDA and AMPA receptors. ## Footnote NMDA detects glutamate and requires depolarisation to open.
34
What is the primary purpose of LTD?
Fine-tuning and forgetting. ## Footnote LTD helps to rebalance synaptic strength.
35
What is non-associative learning?
Learning without pairing two stimuli. ## Footnote An example is sensitisation.