Lec 1

Question 1

What is RBC count ?

Answer 1

Number of red blood cell in specific volume of blood

Question 2

Hemoglobin count ? (HGB)

Answer 2

Amount of hemoglobin in specific volume of blood

Question 3

What is hematocrit (HCT) ?

Answer 3

Ratio of RBCs in whole blood

Question 4

What is the packed cell volume (PCV)?

Answer 4

Same hematocrit

Question 5

What is mean corpuscular volume ?(MCV)

Answer 5

Average volume of RBCs

Question 6

What is the unit of MCV?

Answer 6

Femtoliter

Question 7

What is the most important RBCs index ?

Answer 7

Mean corpuscular volume

Question 8

What is the normal value of MCV?

Answer 8

80-100 femtoliter

Question 9

What is the macrocytic RBCs?

Answer 9

Large volume of RBCs (more than 10p femtoliter)

Question 10

What is the microcytic RBCs?

Answer 10

Low volume of RBCs (less than 80 femtoliter)

Question 11

What is the mean corpuscular hemoglobin?

Answer 11

Hemoglobin per RBC

Question 12

What is the unit of MCH?

Answer 12

Picogram

Question 13

What is the mean corpuscular hemoglobin concentration?

Answer 13

Concentration of hemoglobin in packed blood or in hematocrit

Question 14

What is hyperchromic ?

Answer 14

Highly hemoglobin in RBCs (hight MCHC)

Question 15

What is hypochromic?

Answer 15

Low hemoglobin in RBCs (low MCHC)

Question 16

What is red cell distribution width (RDW)

Answer 16

Measures the vibration in size of RBCs

Question 17

What is anisocytosis?

Answer 17

Variation of size of RBCs

Question 18

Where we detected high reticulocyte count?

Answer 18

And thing lead to hemolysis and in acute blood loss

Question 19

Where we see low reticulocyte ?

Answer 19

Disease in bone marrow or depression in bone marrow due to other disease or drug

Question 20

What is the normal range of hemoglobin in male & female?

Answer 20

13.5 in male & 12 in female

Question 21

What is the functional classification of anemia?

Answer 21

Blood loss , decreased RBCs production , hemolytic anemia

Question 22

What is the morphological calssification of anemia?

Answer 22

1-microcytic anemia
2-normocytic anemia
3-macrocytic anemia

Question 23

What is the cause of microcytic anemia ?

Answer 23

Iron deficiency, thalassemia, may be anemia of chronic disease , sideroblastic anemia

Question 24

What is the cause of normocytic anemia ?

Answer 24

Hemolysis , acute blood loss , anemia of chronic disease

Question 25

What is the cause of macrocytic anemia ?

Answer 25

1-megaloblastic anemia B12 & folate deficiency, drugs or toxin 2-non-megaloblastic anemia Chemotherapy, aplastic anemia, drug or toxin

Question 26

What is the irons storage pool?

Answer 26

Hemosiderin & ferritin

Question 27

What is the good measure of iron store

Answer 27

Ferritin

Question 28

How iron transport?or which protein use to transport iron?

Answer 28

Transferrin protein

Question 29

What is the cause of iron deficiency?

Answer 29

Poor nutrition intake , blood loss , increase demand , malabsorption

Question 30

What is the change that occurs with iron deficiency anemia?

Answer 30

Low serum ferritin & iron | Hight transferrin & hight TIBC

Question 31

What is the change that occurs in RBCs in iron deficiency anemia?

Answer 31

``` 1-hypochromic RBCs 2-microcytic RBCs 3-anisocytosis 3-poikilocytosis 4-low reticulocyte ```

Question 32

What is poikilocytosis?

Answer 32

Variation in shape of RBCs

Question 33

What is the change occurs in peripheral blood in megaloblastic anemia?

Answer 33

Egg shape RBCs (Macrocytic) | Hypersegmented neutrophils and large platelets

Question 34

What is the change occurs in bone marrow in megaloblastic anemia?

Answer 34

Hyper cellular , megaloblastic erythroid progenitor, giant metamyelocytes , abnormal large megakaryocytes