Lec 3 Flashcards

1
Q

what does a research study try to do

A

tries to answer a question

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2
Q

what is the one aim of a research study

A

to underpin the understanding of clinical research methods relevant to the practising optometrist (wants us to have that knowledge)

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3
Q

what is the aim of experiments in clinical research

A

proving or contradicting a hypothesis with data (to prove something is best clinical practice)

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4
Q

what are experiments in clinical research interested in

A

an outcome (dependent) which may be influenced by an attribute (independent)

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5
Q

what did john snow do a experiment in

A

the cholera epidemic in london - the link between cholera and drinking water

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6
Q

what year did john snow carry out his experiment

A

1854

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7
Q

what is an epidemiology

A

the study of causes and risk factors of a certain disease, or someone getting the disease

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8
Q

what does a epidemiology prove

A

if a certain treatment will work

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9
Q

what is the purpose of evidence based medicine

A

to apply the best available evidence gained from the scientific method to medical decision making
(about collecting information and data to support a hypothesis)

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10
Q

what does evidence based medicine (EBM) seek to assess

A

the quality of evidence of the risks and benefits of treatments (including lack of treatment)

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11
Q

which two bodies is EBM used by

A

NHS and NICE

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12
Q

what does NICE do

A

it publishes clinical appraisals of whether particular treatments should be considered ‘worthwhile’ by the NHS

it decides what search evidence to be used in the clinical domain and decides what healthcare service is affordable, so they decide on the costs and benefits of treatments

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13
Q

why is EBM important for optometrists too

A

as we are primary clinical care providers e.g. with the OCT, research study was done to decide if its a good tool to use e.g. in AMD etc

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14
Q

what two types of research is EBM found in

A

primary and secondary

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15
Q

where does primary research come from

A

the researchers themselves written in journal articles/research papers

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16
Q

what is a primary research an outcome of

A

a single study

17
Q

how is a primary research publication determined

A

it is peer reviewed (two people decide if the research study should get published and the peers are anonymous)

18
Q

give two examples of methods to conduct primary research

A

experimental studies (clinical trials) and observational studies

19
Q

what is a secondary research

A

a research that summarises findings of multiple trials, experiments or surveys on the same topic

it looks at how other people try to answer the same question by looking at sources of primary research

20
Q

which company publishes 5,000 medical articles per day

A

biomedical

21
Q

how many articles does the medline publish per day

A

1,500

22
Q

which company publishes 95 medical articles per day

A

trials

23
Q

who is NHS evidence managed by

A

national institute for health and clinical excellence - NICE

24
Q

what can vary between scientific and research papers

A

the quality of the scientific journals

25
Q

what does ‘impact factor’ mean with scientific and research papers

A

how many people read the paper and if its sighted with any clinical meaning, the papers are ranked every year according to this

26
Q

what is google scholar a good tool for

A

most recent research, which is important

27
Q

what does the research articles in google scholar also show you

A

how much the paper has been sighted = the amount of people that contributed to the paper…the more the better

28
Q

how is the type of primary research: observational study carried out

A

the investigator has no control over exposures to risk of treatments and instead observes what happens to groups of people

29
Q

how is the type of primary research: experimental studies (clinical trials) carried out

A

conditions are under the direct control of the investigator

30
Q

what are experimental studies on humans called

A

clinical trial

31
Q

what is a clinical trial the best method for

A

to decide if a treatment is good enough to work