lecture 09-10

Question 1

higher efficacy SNRI or SSRI

Answer 1

SNRI

Question 2

Higher acceptability SSRI, SNRI, TCA?

Answer 2

1. SSRI
2. SNRI
3. TCA

Question 3

Pharmacology vs psychotherapy

Answer 3

1970s-80s suggest both just as effective,
in anxiety: except for OCD, similar results at the end of treatment for both
Same for MDD, but long term showed CBT had a stronger lasting effect

Question 4

is there a difference in placebo, SSRI, and other antidepressants

Answer 4

no sig difference

Question 5

are suicide and anti-depressants related

Answer 5

failure to adequatley treat a mood disorder will lead to suicidability vs the drug being the cause.

Question 6

What is the MA hypothsis of depression

Answer 6

reduced MA levels in the brain reduce depression

Question 7

How was the MA hypothessi found?

Answer 7

reseprine drug created more MA in the synapses and caused depression

Question 8

refinement of MA hypothsis

Answer 8

propose that different receptor subtypes might be differentially related to depression, some viewed a pro-depressant and soem as anti