Lecture 1

Question 1

Total Body Water?

Answer 1

(Body Fluids)
-Varies from 50-70% of body weight
-Average person is about 42 kg or 42 L

Question 2

(Percentage of Water in Tissues)
Skin?

Answer 2

-72% of water
-18% of body weight
-9.1 L of water

Question 3

(Percentage of Water in Tissues)
Muscle?

Answer 3

-76% of water
-41.7% of body weight
-22.1 L of water

Question 4

Tissues that make up most of body H2O?

Answer 4

Skin and Muscle

Question 5

Which Tissue is susceptible to edema?

Answer 5

Brain

Question 6

Which Tissue is the least because of hydrophobicity?

Answer 6

Adipose Tissue

Question 7

Intracellular (ICF)?

Answer 7

-40% of body weight
-28 L

Question 8

Extracellular (ECF)?

Answer 8

-20% of body weight
-14 L

Question 9

Plasma?

Answer 9

-4-5% of body weight
-25% of ECF

Question 10

Interstitial?

Answer 10

-75% of ECF

Question 11

What makes up the ECF?

Answer 11

Interstitial + Plasma

Question 12

2/3 of TBW?

Answer 12

ICF

Question 13

1/3 of TBW?

Answer 13

ECF

Question 14

What can pass through cell membrane?

Answer 14

Only water

Question 15

What wall is very permeable?

Answer 15

Capillary Wall

Question 16

ECF + ICF = ?

Answer 16

TBW

Question 17

(Measuring the Size of Compartments)
TBW?

Answer 17

(Radio-Labeled H2O)
HTO and D2O

Question 18

(Measuring the Size of Compartments)
ECF?

Answer 18

-Inulin (only in ECF)
-Radio-sodium

Question 19

(Measuring the Size of Compartments)
Plasma?

Answer 19

-I-albumin
-Evans Blue

Question 20

(Measuring the Size of Compartments)
Blood?

Answer 20

Cr-RBCs

Question 21

(Measuring the Size of Compartments)
Interstitial?

Answer 21

-Indirect
-(ECF - Plasma)

Question 22

(Measuring the Size of Compartments)
ICF?

Answer 22

-Indirect
-(TBW - ECF)

Question 23

Standard Equation?

Answer 23

Compartment Volume = (Amount Injected) / (Final Concentration)

Question 24

Molar Concentration?

Answer 24

(# of atoms or charge of ion) x (mmol/L)

Question 25

Plasma Electrolyte Total?

Answer 25

300 mOsmoles/L of H2O

Question 26

Osmolality?

Answer 26

millimoles of solute/kg of H2O

Question 27

Osmolarity?

Answer 27

millimoles of solute/L of H2O

Question 28

Activity of H2O decreases as?

Answer 28

Osmolality increases

Question 29

Colligative Properties of Solutions depend on?

Answer 29

Number of molecules and not their nature -Boiling Point -Freezing Point -Vapor Pressure -Osmotic Pressure

Question 30

Decrease due to lots of protons (because HCl)?

Answer 30

Vomiting

Question 31

Decrease due to lots of bicarb?

Answer 31

Diarrhea

Question 32

(Daily Turnover of Fluids) Infant?

Answer 32

-2.3 L of TBW (77%) -16 (1/6)

Question 33

(Daily Turnover of Fluids) Adult?

Answer 33

-42 L of TBW (60%) -6 (1/16)

Question 34

Na primarily in?

Answer 34

Areas after the stomach

Question 35

Cl primarily in?

Answer 35

Saliva and Gastric Juices

Question 36

ECF cation is?

Answer 36

Na

Question 37

ECF anion is?

Answer 37

Cl- (and HCO3-)

Question 38

ICF cation is?

Answer 38

K+

Question 39

ICF buffer is?

Answer 39

H2PO4-