Lecture 1 Flashcards

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1
Q

What does Sexually dimorphic mean?

A

Males and females are physically different

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2
Q

3 elements that male and female reproductive systems have in common?

A
  1. General process 2. production of hormones. 3. maturation of reproductive capabilities
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3
Q

What are the male gonads?

A

Testes

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4
Q

What are the female gonads?

A

ovaries

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5
Q

What are the sex cells produced by the testes and ovaries

A

Spermatozoa for males and oocytes for females (stem cells)

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6
Q

What is sexual reproduction?

A

a process where a genetically novel individual is formed as a result of mixing genes from two individuals

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7
Q

What is a hormone?

A

internal molecular messenger

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8
Q

What is the importance of hormones in reproductive physiology

A

They regulated all aspects of reproduction.

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9
Q

What are the roles that hormones play in both males and females?

A

FSH and LH

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10
Q

what are the structures/ organs that have endocrine function

A

the hypothalamus, anterior pituitary gland, gonads, pineal gland and placenta.

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11
Q

what is a paracrine?

A

A hormone that acts on a neighboring cell.

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12
Q

How are hormones structurally classified?

A

Water soluble ( protein/peptide hormones) and lipophilic ( steroid hormones and fatty acid hormones)

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13
Q

All steroids are derived from?

A

Cholesterol

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14
Q

what are the 3 classes of sex steroid hormones ?

A

Androgens, estrogens, and progesterone.

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15
Q

What is a ligand

A

a molecule that binds to a receptor. Hormones are ligands.

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16
Q

list the male and female hormones that belong to the class of peptide/protein hormones?

A
17
Q

How does the location of a receptor for a protein hormone vs a steroid hormone

A

protein receptors are on the cell membrane and steroid hormones are inside the cell

18
Q

Describe the mechanism of action of a peptide-protein hormone

A

use a second messenger to carry out its function.

19
Q

how is upregulation different from downregulation

A

too much chemical => down regulated, and too little => up regulation.

20
Q

What is the mechanism of a steroid hormone

A

Diffuse through the phospholipid membrane.

21
Q

what does affinity mean?

A

strength of receptor and ligand binding.

22
Q

how can a receptor have different affinities?

A

external factors.

23
Q

what is the role of sex steroid binding globulin ?

A

It transports lipophilic hormones through the blood.

24
Q

what are the factors that determine the responsiveness of a target cell to a hormone ?

A

Blood concentration, receptor density, receptor sensitivity ( affinity) , and hormone interactions.

25
Q

what are the 3 modes of hormone secretion?

A

Pulsatile, circadian , episodic

26
Q

describe the analogs of FSH/LH levels and fertility

A

GnRH is an analog as both agonist and antagonist. GnRH continuously decreases LH and FSH and GnrH pulsatile release stimulates LH and FSH.

27
Q

what 3 sets of structures make up the sex organs of both males and females?

A

Gonads, internal genitalia
, external genitalia

28
Q

What is an exocrine gland?

A

Glands that secrete hormones or chemicals into ducts. Example sweat glands.

29
Q

an example of a paracrine

A

Prostaglandins

30
Q

describe the mechanism of action of a peptide-protein hormone

A

Us a secondary messenger to enter the cell or signal to the cell.

31
Q

What are the 3 modes of hormone secretion?

A

Hormonal , humoral , neural