Lecture 1 Flashcards
(11 cards)
Microbe
Needs Microscope
Single / Multicellular
Metabolize food, grow and self reproduce
They also have proteins, sugars, genomes made of nucleic acid
Bacteria range
Average bacteria
0.125um to 80 um to 750 um
1um; 2-4 um. (E.coli)
6 major groups of Microbes
Prokaryotes —> 1. Bacteria 2. Archaea
Eukaryotes —> 3. Algae 4. Protists 5. Fungi
Viruses
Non cellular and use another’s cells machinery to generate more virus particles
(They still have genetic content)
DNA Sequencing
Influences study of Microbes
First DNA Sequencing Method
Developed by Fred Sanger
Genome —> total genetic material
Prokaryotes— 180,000
Eukaryotes— 7,000
Viruses — 23,000
E. Coli and B. Fragilis
E.coli and Fragilis
Share 40% of their genes
C.elegins and H. Sapiens
Share 38% of genes
Microbial disease in warfare
-who found the science of medical stats
- More soilders have died from microbial infection than battle wounds
- Nurse Florence Nightgale
Robert Hook
- Built first compound microscope (30x)
- Saw mold
- 1st to see units of living materials “cells”
- Never saw single-celled Bacteria
Antonie van Leeuwenhoek
- 1st to see single-celled microbes
- Used a single lens
- Saw microbes from the matter between his teeth before and after drinking coffee
* Microbes disappeared after drinking coffee which suggested that heat killed them