Lecture 1 Affective Disorders Flashcards

(28 cards)

1
Q

Name examples of Affective (Mood) disorders

A

Depression

Bipolar

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2
Q

When does depression become abnormal

A

No clear and convenient division

Persistence

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3
Q

What is depression

A

An unpleasant emotion in which sadness or unhappiness predominates for at least 22 weeks

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4
Q

What is agitation

A

A state of restless overactivity, aimless or ineffective

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5
Q

What is anhedonia

A

Loss of ability to derive pleasure from experience

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6
Q

What is apathy

A

Loss on interest in own surroudings

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7
Q

What is anxiety

A

An unpleasant emotion in which thoughts of apprehension or fear predominate

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8
Q

What is retardation

A

A slowing or motor responses including speeh

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9
Q

What is stupor

A

A state of extreme retardation in which consciousness is intact

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10
Q

Describe the symptoms of depression- Somatic syndrome

A
Apathy
Anhedonia
Waking early
Worse in morning
Marked loss of appetite
Marked loss of libido
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11
Q

Mild depression includes at least how many of these symptoms

  • Loss of confidence or self esteem
  • Unreasonable feelings of guilt or self reproach or excessive guilt
  • Recurrent thoughts of death by suicide or any suicidal behaviour
  • Decreased concentration
  • Agitation or retardation
  • Sleep disturbance of any sort
  • Change in appetite
A

4

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12
Q

Moderate depression includes at least how many of these symptoms

  • Loss of confidence or self esteem
  • Unreasonable feelings of guilt or self reproach or excessive guilt
  • Recurrent thoughts of death by suicide or any suicidal behaviour
  • Decreased concentration
  • Agitation or retardation
  • Sleep disturbance of any sort
  • Change in appetite
A

6

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13
Q

Severe depression includes at least how many from these list

  • Loss of confidence or self esteem
  • Unreasonable feelings of guilt or self reproach or excessive guilt
  • Recurrent thoughts of death by suicide or any suicidal behaviour
  • Decreased concentration
  • Agitation or retardation
  • Sleep disturbance of any sort
  • Change in appetite
A

8

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14
Q

What are the differential diagnosis of depression

A
Normal reaction to life event
SAD
Dysthymia
Cyclothymia
Bipolar
Stroke, tumour, dementia
Hypothyroidism, Addisons
Drugs
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15
Q

What is the treatment for mild depression

A

Monitoring, self help, CBT, exercise

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16
Q

What is the treatment for moderate depression

A

Anti-depressant (first line SSRI), CBT

17
Q

What is the treatment for severe depression without psychotic features

A

Anti-depressant medication plus CBT

18
Q

What is the treatment for severe depression with psychotic features

A

Anti-depressant + Antipsychotic

19
Q

If there is treatment refractory in depression what is the next step

A

Switch anti-depressant or augment with lithium/antipsychotic

20
Q

Name measurement tools for depression

A
SCID
SCAN
HDRS
BDI-II
HADS
PHRQ-9
21
Q

What is mania

A

A psychological condition that causes a person to experience unreasonable euphoria, very intense moods, hyperactivity, and delusions

22
Q

What are the features hypomania

A

Lesser degree of mania
No psychosis
Elevation of mood, energy, sociability, talkativeness, libido
Decreased need for sleep
Normal life disrupted but ca still function

23
Q

How long can mania last

A

At least 1 week

24
Q

What are the features of mania

A
Severe disruption to ordinary work and social activities
Elevation of mood, energy, sociability, talkativeness, libido
Decreased need for sleep
Disinhibition
Grandiosity
Alteration of senses
Extravagant spending 
Psychotic symptoms
25
Wha is Bipolar Affective Disorder
Consist of repeated episodes of depression and mania or hypomania
26
What is the treatment for Bipolar in the acute phase
If they are on anti-depressants stop them | Anti-psychotics (Olanzapine, Quetiapine or Risperidone) for at least 2 years
27
If response to antipsychotics drugs in BP is inadequate what can be added
Lithium | Sodium valproate
28
What is Benzodiazepines used for
Useful in the initial stages of treatment for behavioural disturbance or agitation (short term)