Lecture 1 Pt 2 Flashcards

1
Q

The ___________ is a complex network of structures and pathways that organize, control and execute voluntary movements

A

sensorimotor system

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2
Q

List all the structures involved in the sensorimotor system

A
  • cortex and UMNs
  • subcortical structures: basal ganglia, cerebellum
  • brainstem
  • LMNs - cranial and spinal nerves
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3
Q

What structure/area of the brain generates neural impulses that control execution of movements

A

the primary motor cortex

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4
Q

If motor movements are internally driven (initiation, maintenance, inhibition and learning of complex motor behaviours) they are driven by what area of the brain

A

Supplementary motor area

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5
Q

If motor movements are sensory guided (externally driven) they are driven by what area of the brain?

A

Premotor cortex

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6
Q

Describe the key aspects of the primary motor cortex

A
  • somatotopically organized
  • control voluntary muscles on contralateral side
  • # of motoneurons allocated to a muscle depends on the degree of control needed
  • Organized in FUNCTIONAL groups
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7
Q

Damage to motor areas in the cortex would likely lead to what type of MSDs

A

unilateral UMN dysarthria and spastic dysarthria

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8
Q

Damage to broca’s area, left insula or arcuate fasciculus would likely lead to what type of MSD

A

apraxia of speech

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9
Q

List the divisions of UMNS

A
  • Pyramidal tract (2 subtracts, corticospinal and corticobulbar)
  • Extrapyramidal tract
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10
Q

Describe UMNs

A
  • contained within CNS
  • originate in the cortex
  • terminate @ cranial or spinal nerve nuclei
  • include pyramidal and extrapyramidal tracts
  • don’t include BG and cerebellar control circuits
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11
Q

What is the function of UMNs?

A

control voluntary movements (finely controlled, skilled, discrete, rapid)

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12
Q

How many axonal synapses do UMNs have?

A

1

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13
Q

UMN innervate LMNs on the _______ side of the body

A

contralateral/opposite

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14
Q

List the UMN effects of damage

A
  • Hypertonia (spasticity)
  • Hyperreflexia
  • Emotional lability
  • Weakness
  • Babinski sign
  • Spastic or unilateral UMN dysarthria
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15
Q

Define hypertonia - spasticity

A

an increase in muscle tone due to hyperexcitability of the stretch reflex; characterized by a velocity-dependent increase in tonic stretch.

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16
Q

When analyzing someone’s speech what are the 2 channels from which we get info?

A

-visual and auditory

17
Q

Pseudobulbar palsy involves damage where?

A

in multiple UMNs that feed into multiple cranial nerves

18
Q

Describe LMNs

A
  • contained within CNS and PNS
  • originate in the brainstem and spinal cord
  • terminate at the muscle
  • carry out UMN commands for voluntary movements
  • produce muscle actions in reflexes
  • somewhat responsible for maintaining muscle tone
19
Q

List LMN effects of damage

A
  • hypotonia
  • atrophy
  • hyporeflexia
  • weakness (paralysis)
  • fasciculations
  • flaccid dysarthria
20
Q

Bulbar palsy involves damage where?

A

damage in multiple LMNs

21
Q

What type of degeneration is present in ALS?

22
Q

What type of degeneration is present in primary lateral sclerosis

23
Q

What type of degeneration is present in PSP

24
Q

What type of degeneration is present in progressive muscular atrophy?

25
What type of degeneration is present in progressive bulbar palsy
LMN
26
What are common signs in ALS (related to SLP)s?
- Tongue fasciculations, increased jaw jerk, tongue atrophy, dysarthria & dysphagia - Slowing of speech rate (cardinal sign) - Decreased intelligibility
27
What will be the result of a phrenic nerve lesion below c5?
many abdominal and thoracic muscles involved in breathing but diaphragm is ok
28
What will be the result of a phrenic nerve lesion between C3 and C5?
cause paresis of the diaphragm – will need help with breathing
29
What will be the result of a phrenic nerve lesion above C3?
paralyzed diaphragm – ventilator
30
List the relevant muscles for inspiration and expiration
- sternocleidomastoid - external intercostals - internal intercostals - diaphragm - rectus abdominis - external oblique - internal oblique - transvers abdominus
31
Where is the CPG that controls respiration located?
brainstem
32
In order for the cortex to control voluntary breathing, what must be overridden?
- the brainstem respiratory CPG
33
Describe myasthenia gravis
- An autoimmune disorder in which the body produces antibodies that block ACh receptors at the post-synaptic neuromuscular juncture - Leads to weakness and fatigue esp. in head and neck - No atrophy or fasciculations - Increased weakness with increased use