Lecture 10 Flashcards

1
Q

Binary Fission

A

Simpler than mitosis due to lack of membrane bound organelles and only 1 chromosome, prokaryote only

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2
Q

Lag Phase

A

Cells are growing but not dividing, replication and metabolism

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3
Q

Log Phase

A

Cells are dividing

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4
Q

Stationary Phase

A

Max population, cell division equals cell death, nutrients and space are limiting

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5
Q

Death Phase

A

Cells die due to an accumulation of waste and lack of ressources

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6
Q

Chromosome

A

Molecule of genetic information

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7
Q

Chromatid

A

Product of DNA replication

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8
Q

Centromere

A

Site of attachment for sister chromatids, site of kinetochore assembly

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9
Q

Kinetochore

A

Protein complex at centromere

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10
Q

G1 Phase

A

Gap 1 phase, normal cell activities, cell is dividing to decide (whether conditions can support 2 daughter cells)

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11
Q

S Phase

A

Synthesis phase, DNA replicates

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12
Q

G2 Phase

A

Gap 2 phase, normal cell activities with twice the amount of DNA

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13
Q

Mitosis

A

Separation of sister chromatids

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14
Q

Interphase

A

All phases where cell is not actively dividing (G1, S and G2)

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15
Q

Prophase

A

Packaging of chromosomes into mitotic chromosomes , (condensation of chromosomes)

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16
Q

Prometaphase

A

Nuclear envelope break down, microtubules invade nuclear area and attach to kinetochores

17
Q

Metaphase

A

Chromosomes line up on metaphase plate

18
Q

Anaphase

A

Separation of chromatids (chromatids become chromosomes)

19
Q

Polar microtubules

A

Microtubules bound to other microtubules, use kinesin to elongate cell

20
Q

Astral microtubules

A

Microtubules bound to plasma membrane, prevent MTOC from moving to centre of cell

21
Q

Kinetochore microtubules

A

Pull chromosomes to poles via depolymerization & dynein

22
Q

Telophase

A

Chromosomes decondense and nuclear envelope reforms, start of cytokinetic furrow

23
Q

Cytokinesis

A

Separation of cytoplasm

24
Q

Contractile Ring

A

Cytokinetic furrow, formed by microfilaments and contracted by myosin

25
Cancer
Uncontrolled cell division due to accumulation of mutations
26
Tumour Suppressor Genes
Proteins that prevent passage through cell cycle
27
Proto-oncogenes
Promote passage through cell cycle