Lecture 10 Flashcards
(33 cards)
Stress response
- The physiological changes that occur when you experience a stressor
- Complex network of nerve signalling and hormonal messaging which activates some physiological processes and suppresses others
- A way in which individuals regulate their physiology in response to daily activities and environmental conditions
Stressor
.Anything that activates / elicits a stress response (usually threats to survival or reproduction)
Hans Selye
. Describe the “general adaptation syndrome” as a predictable way that the body responds to stress
general adaptation syndrome
- The predictable way the body responds to stress
- Described by Hans Selye
- 3 stages: alarm, resistance, and exhaustion
- fight or flight response
- focus resources against stressor
- if stress prolonged or beyond capacity, body exhausts itself
allostasis
the normal range for a physiological system varies by circumstances in an adaptive fashion
-process by which body reacts to stress in order to maintain homeostasis
allostatic load
the costs associated with the negative health outcomes of a prolonged stress response
-“wear and tear” of chronic stress.
autonomic nervous system
the part of the nervous system responsible for control of the bodily functions not consciously directed, such as breathing, the heartbeat, and digestive processes.
sympathetic nervous system
-activates stress response
parasympathetic nervous system
-suppresses stress response.
adrenal gland
-secretes epinephrine (adrenaline), located just above kidneys
hormonal stress response
- threat perception by brain
- release of corticotrophin-releasing hormone by hypothalamus
- secretion of ACTH/corticotropin by pituitary gland (HPA axis)
- circulation of ACTH in the bloodstream triggering the release of cortisol by the adrenal gland
- cortisol receptors in brain structures such as the hippocampus can stimulate further cortisol release
cortisol
Cortisol is a steroid hormone that regulates a wide range of processes throughout the body, including metabolism and the immune response. It also has a very important role in helping the body respond to stress.
HPA axis
complex set of direct influences and feedback interactions among three components: the hypothalamus, the pituitary gland, and the adrenal.
-component of major neuroendocrine system
EAA in relation to stress response
- environment of evolutionary adaptedness
- persistent activation of stress response as result of thinking a lot and complex/stressful contemporary social situations
- these issues happen because we are maladapted to our modern stress environment
Stress in humans
stress and biological normalcy
- studies about stress in many areas, such as those in th US, tend to be biased, especially towards having highly stressed individuals be presented as the norm rather than as pathologic
- cadavers used to study were historically from working class rather than upper clas
CVD and stress
- heart is one of the main targets of epinephrine
- receives indirect effects from cortisol
- increased risk of CVD asociated with stress
- changes in blood pressure (hypertension), possibility of heart attack and stroke
immune function and stress
-cortisol causes IMMUNOSUPPRESSION in the form of thymus shrinkage, lowered circulating T-cell levels, reduced cytokine levels, and the inhibition of antigen presentation
-can become pathological over time
-tied to chronic stress
EX) getting sick during exam season
immunosuppression
-the partial or complete suppression of the immune response of an individual.
autoimmune
-is the system of immune responses of an organism against its own healthy cells and tissues. Any disease that results from such an aberrant immune response is termed an “autoimmune disease”`
child growth and stress
- can occur at any point in growth and development
- in utero experience influences development of the HPA response
- impaired growth
- accelerated development
- influence of security and attachment
- extreme end results in psychosocial dwarfosm
attachment and stress
-formation of attachment anxiety and avoidance
delayed growth and stress
-stress sends a signal to delay physical growth
accelerated development and stress
- accelerated sexual develop and maturity
- lower age at which can bear children and in turn maximize change at reproducing