Lecture 10: Psychosis Flashcards

(60 cards)

1
Q

What does the term “psychosis” refer to?

A

Psychosis refers to some loss of contact with reality, with altered perception, thoughts, mood, and behavior.

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2
Q

What is the lifetime prevalence of psychosis?

A

The lifetime prevalence of psychosis is about 3%.

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3
Q

What is the treatment gap for schizophrenia internationally?

A

The treatment gap for schizophrenia is about 30%.

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4
Q

At what age does schizophrenia typically onset for men and women?

A

Schizophrenia typically onsets in adolescence for men and middle age for women.

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5
Q

What are common co-morbid conditions associated with schizophrenia?

A

Co-morbid conditions include substance abuse, depression, anxiety, suicide, and chronic medical disorders like HIV and diabetes.

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6
Q

What are the DSM-5 criteria for diagnosing schizophrenia?

A

The criteria include 2 or more symptoms: delusions, hallucinations, disorganized speech, disorganized or catatonic behavior, and negative symptoms, with a duration of at least 6 months.

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7
Q

How long must symptoms persist for a schizophrenia diagnosis?

A

Symptoms must persist for at least 6 months, with active symptoms lasting for 1 month.

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8
Q

What exclusions must be ruled out in diagnosing schizophrenia?

A

Schizoaffective disorder, depressive/bipolar disorders with psychotic features, or substance abuse.

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9
Q

What is the difference between schizophrenia and schizoaffective disorder?

A

Schizoaffective disorder shows higher scores for mania and depression.

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10
Q

What is schizoaffective disorder?

A

It involves features of schizophrenia combined with a mood disorder episode (either depression or mania).

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11
Q

How long do symptoms last for schizophreniform disorder?

A

Symptoms last at least 1 month but less than 6 months, making it schizophrenia-like but not a full diagnosis.

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12
Q

What is the key feature of delusional disorder?

A

It involves delusional beliefs (false beliefs) with otherwise normal behavior, such as erotomania (believing someone of higher status loves them).

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13
Q

How long do symptoms last in brief psychotic disorder?

A

Symptoms last more than 1 day but less than 1 month.

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14
Q

What defines schizotypal personality disorder?

A

It involves stable, mild psychotic traits that are consistent across time and situations, but the individual remains in contact with reality.

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15
Q

What are the early symptoms of prodromal psychosis?

A

Symptoms include negative symptoms (e.g., reduced expressiveness) or mild positive symptoms (e.g., delusions, hallucinations) in attenuated form.

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16
Q

What is the hallmark symptom of hallucinations in psychosis?

A

Hallucinations are sensory experiences that feel real but occur without any external perceptual stimulus, and auditory hallucinations are the most common.

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17
Q

What might people think when they experience hallucinations or psychosis?

A

People might think it’s no big deal, be mildly amused, wonder if they are going crazy, or feel the need to investigate further.

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18
Q

What are the typical characteristics of voices in auditory hallucinations?

A

Voices can originate from the ears, mind, surface of the body, or external space. They vary in frequency (from rare to constant), loudness (whispers to shouts), and may have different accents. The voices may discuss behavior or express emotions (negative or positive).

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19
Q

How do patients emotionally react to their hallucinations?

A

Patients often emotionally engage with their hallucinations and might incorporate them into delusions.

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20
Q

What is a delusion?

A

A delusion is a false, fixed belief that cannot be changed even when presented with conflicting evidence. It often involves disturbances in thought, external control of thoughts, or neutral events having personal relevance.

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21
Q

How do delusions compare to normal beliefs in recent views?

A

Delusions are now seen as more like strong normal beliefs, maintained with little evidence, and they persist despite conflicting evidence. They involve confirmation bias and ignoring contradictions.

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22
Q

What is an example of how delusions are similar to normal beliefs?

A

An example is the Flat Earth theory—if enough people believe the same thing, it is treated as a normal belief.

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23
Q

What is the Paranoia Hierarchy?

A

The Paranoia Hierarchy classifies perceived threats into levels: severe, moderate, and mild threats, as well as ideas of reference and social evaluative concerns.

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24
Q

What does severe paranoia involve in the hierarchy?

A

Severe paranoia includes concerns about significant harm, such as conspiracy theories or beliefs that people are out to cause physical, psychological, or social harm.

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25
What is an example of mild paranoia?
Mild paranoia involves fears that people are trying to cause minor distress, such as irritation.
26
What is disorganized speech?
Disorganized speech occurs when language is used conventionally but fails to make sense, leaving the listener confused. It may involve creating new words (neologisms).
27
What is catatonia?
Catatonia involves almost no movement at all, and sometimes unusual postures. It can also present as catatonic stupor, a near-total absence of movement and speech.
28
What are positive symptoms in psychosis?
Positive symptoms involve an excess or distortion of normal behaviors and experiences, such as delusions, hallucinations, and disorganized speech.
29
What are negative symptoms in psychosis?
Negative symptoms reflect an absence of normal behavior, such as reduced expressive behavior and avolition (lack of motivation to complete tasks).
30
What is avolition?
Avolition refers to the inability to initiate or persist in goal-directed activity, such as not completing daily tasks.
31
What is the medical model of psychosis?
The medical model views psychosis as a lifelong disorder traditionally treated only with medication, with limited psychological intervention due to symptoms being seen as un-understandable.
32
How does schizophrenia relate to genetics?
Schizophrenia is familial and tends to run in families. First-degree relatives have a 10% risk of developing it, while second-degree relatives have a 3% risk.
33
What is the difference between familial and genetic factors in schizophrenia?
Familial means the disorder appears in families, but it may not always be due to genetic factors. Nongenetic reasons can also contribute to familial patterns.
34
What is the risk of developing schizophrenia for identical twins?
Identical twins, sharing 100% of genes, have about a 50% risk of developing schizophrenia.
35
What is the risk of developing schizophrenia for fraternal twins?
Fraternal twins, sharing 50% of genes, have a risk of around 15-20% for developing schizophrenia.
36
What do twin studies reveal about schizophrenia?
Identical twins have a 28% concordance rate for schizophrenia, higher than fraternal twins (6%), indicating that genetic factors play a role, but other factors also contribute.
37
What do adoption studies show about schizophrenia?
Children with schizophrenic biological parents who are adopted into other families have higher rates of schizophrenia, showing that genetic factors influence the risk.
38
How does the adoptive family quality affect the risk of schizophrenia?
Children with high genetic risk raised in healthy environments develop fewer problems than those raised in unhealthy environments, highlighting the influence of genotype-environment interaction.
39
What is the neurodevelopmental perspective on schizophrenia?
Schizophrenia begins early in life, with prodromal symptoms appearing before the illness is diagnosable. Attenuated psychosis syndrome is part of DSM-5 for further study.
40
What brain abnormalities are associated with schizophrenia?
Schizophrenia is linked to cognitive impairment, which is present before diagnosis. Lower IQ may increase the risk, and patients have difficulties in responding to stimuli quickly, with early deficits in visual and auditory processing.
41
What is the eye tracking pattern difference in schizophrenia?
People with schizophrenia show abnormal eye tracking compared to normal tracking, which can be identified through patterns that are disrupted and irregular.
42
What is social cognition and how does schizophrenia affect it?
Social cognition is how we perceive and respond to social information, including emotions. Schizophrenia leads to impairments, making it hard for individuals to recognize emotions and spot social cues.
43
What are the effects of brain volume loss in schizophrenia?
Schizophrenia causes enlarged brain ventricles, with male patients more affected. The reduced brain tissue is a sign of early and progressive deterioration.
44
How does schizophrenia affect white matter?
White matter helps brain connectivity. Abnormalities are linked to cognitive issues and schizophrenia.
45
How does brain development in adolescence relate to schizophrenia?
Major brain changes during adolescence may lead to schizophrenia, especially with head injuries during this time.
46
What role does dopamine play in schizophrenia?
Dopamine is involved in schizophrenia. Chlorpromazine blocks dopamine receptors to help treat symptoms.
47
What is the impact of glutamate on schizophrenia?
Abnormal glutamate levels can mimic schizophrenia-like symptoms.
48
How does brain volume relate to schizophrenia?
People with schizophrenia have reduced brain volume and enlarged brain ventricles, especially males.
49
What does the psychological model of psychosis focus on?
It focuses on how psychotic experiences are a response to distress and life interference, emphasizing normal psychological processes.
50
How do cultural factors influence voice-hearing experiences in psychosis?
In different cultures, psychotic experiences such as hearing voices can vary, with some cultures seeing them as friendly, while others may associate them with violent commands.
51
What does the diathesis-stress model explain about psychosis?
The model suggests that genetic vulnerability combined with environmental stress can lead to the development and progression of psychosis.
52
What factors contribute to stress in childhood and adulthood?
Poverty, early exposure to urban environments, migration, abuse, bullying, work stress, debt, and unemployment.
53
How are stress and hallucinations linked?
Stressful life events can trigger or contribute to the development of hallucinations in people with psychosis.
54
What is Expressed Emotion (EE)?
It’s the level of criticism, hostility, warmth, and emotional overinvolvement in family relationships.
55
How does Expressed Emotion affect recovery?
High EE, such as criticism or overinvolvement, is linked to higher relapse rates after hospitalization.
56
How does cannabis use affect psychosis?
Cannabis use after the onset of psychosis can increase relapse rates and worsen symptoms.
57
What happens when cannabis use is discontinued?
Discontinuing cannabis use reduces relapses and improves functioning in people with psychosis.
58
What are the key types of treatment for psychosis recovery?
Pharmacotherapy, Family therapy, Case management, Occupational therapy, Cognitive behavioral therapy.
59
What percentage of patients with psychosis have a favorable recovery outcome?
Around 38% of patients have a favorable recovery outcome.
60
Why do some patients avoid taking their medication for psychosis?
Some patients avoid medication because taking it makes them feel it confirms their mental illness.