Lecture 11: Citric Acid Cycle Flashcards Preview

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Flashcards in Lecture 11: Citric Acid Cycle Deck (3)
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What does the citric acid cycle do?

- completely oxidize the 2-C acetyl group to 2 CO2 with dehydrogenases (removes a hydrogen)
- Along the way you generate 3 NADH, 1 FADH2 (reduced electron carriers), and 1 GTP=ATP


How is FAD?H different from NADH

- FADH is different from NADH based on its redox potential.
- FADH2 is more positive, so electrons flow in that direction from FAD


Electron Transport chain

- occurs in the inner membrane of the mitochondrion (membranes of christae- more SA)
- transforms NADH to ATP
- consists of a series of redox reactions
- NADH gives up a proton and becomes NAD+ (complex I)
- FADH2 becomes FAD (gives up electrons) when in contact with complex II- has less energy so no proton can be pumped at this step.
- This causes conformation change in the protein that allows to move the proton across the gradient