Lecture 1.2: Key biological concepts

Question 1

What are some roles of ATP and GTP in the cell?

Answer 1

• Nucleotide binding
• Hydrolysis
• Phosphorylation

Question 2

What is Nucleotide binding as a role of ATP and GTP in the cell?

Answer 2

Can control protein shape activity and function

Question 3

What is hydrolysis as a role of ATP and GTP in the cell?

Answer 3

• Fast hydrolysis of ATP = Movement (eg motor proteins)
• Slow = Gives a switch activity

Question 4

What is phosphorylation as a role of ATP and GTP in the cell?

Answer 4

• Phosphorylation is adding a phosphate group from ATP to serine, threonine or tyrosine
• Controls protein function