Lecture Flashcards

(72 cards)

1
Q

Second messenger system of the body
Uses chemical messages (hormones)
that are released into the blood

A

Endocrine

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2
Q

Hormones control several major processes

A

Reproduction
 Growth and development
 Mobilization of body defenses
 Maintenance of much of homeostasis
 Regulation of metabolism

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3
Q

Hormones are produced by

A

specialized cells

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4
Q

Cells secrete hormones into

A

extracellular fluids

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5
Q

Amino acid-based hormones

A

Proteins  Peptides  Amines

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6
Q

made from cholesterol

A

steroids

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7
Q

made from highly
active lipids

A

Prostaglandins

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8
Q

Effects Caused by Hormones

A

Changes in plasma membrane permeability or electrical state
 Synthesis of proteins, such as enzymes
 Activation or inactivation of enzymes
 Stimulation of mitosis

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9
Q

Diffuse through the plasma membrane of target cells
 Enter the nucleus
 Bind to a specific protein within the
nucleus
 Bind to specific sites on the cell’s DNA
 Activate genes that result in synthesis of new proteins

A

steroid action hormone

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10
Q

Hormone binds to a membrane receptor
 Hormone does not enter the cell
 Sets off a series of reactions that activates an enzyme
 Catalyzes a reaction that produces a second messenger molecule
 Oversees additional intracellular changes to promote a specific response

A

nonsteroid hormone action

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11
Q

Hormone levels in the blood are maintained

A

negative feedback

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12
Q

Size of a grape
 Hangs by a stalk from the hypothalamus
 Protected by the sphenoid bone
 Has two functional lobes

A

pituitary gland

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13
Q

Anterior pituitary –

Posterior pituitary

A
  1. Gandular tissue
  2. Nervous tissue
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14
Q

General metabolic hormone
 Major effects are directed to growth of
skeletal muscles and long bones
 Causes amino acids to be built into proteins
 Causes fats to be broken down for a source of energy

A

Growth Hormone

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15
Q

Stimulates and maintains milk production
following childbirth

A

Prolactin

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16
Q

Regulates endocrine activity of the adrenal
cortex

A

Adrenocorticotropic hormone

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17
Q

Influences growth and activity of the thyroid

A

Thyroid-stimulating hormone

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18
Q

Regulate hormonal activity of the gonads

A

Gonadotropic hormones

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19
Q

Stimulates follicle development in ovaries
Stimulates sperm development in testes

A

Follicle-stimulating hormone

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20
Q

Triggers ovulation
 Causes ruptured follicle to become the corpus luteum
 Stimulates testosterone production in males

A

Luteinizing hormone

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21
Q

Release of hormones is controlled by releasing and inhibiting hormones produced by

A

hypothalamus

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22
Q

Stimulates contractions of the uterus during
labor
 Causes milk ejection

A

Oxytocin

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23
Q

Can inhibit urine production
 In large amounts, causes vasoconstriction leading to increased blood pressure

A

Antidiuretic hormone

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24
Q

Found at the base of the throat
 Consists of two lobes joined by central
mass or isthmus

A

Thyroid Gland

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25
Thyroid glands produce two hormones:
Thyroid and Calcitonin
26
Composed of two active iodine- containing hormones
thyroxine and triiodothyronine
27
secreted by thyroid follicles
Thyroxin
28
conversion of T4 at target tissues
Triiodothyronine
29
Decreases blood calcium levels by causing its deposition on bone  Antagonistic to parathyroid hormone
Calcitonin
30
Tiny masses on the posterior of the thyroid  Secrete parathyroid hormone  Stimulate osteoclasts to remove calcium from bone and release it into the blood  Stimulate the kidneys and intestine
Parathyroid Glands
31
Two glands of adrenal glands
Cortex and Medulla
32
outer glandular region in three layers
Cortex
33
inner neural tissue region
Medulla
34
Produced in outer adrenal cortex  Regulate mineral content in blood, water, and electrolyte balance  Target organ is the kidney  Production stimulated by renin and aldosterone  Production inhibited by atrial natriuretic peptide Copyright © 2003 Pearson Education, Inc. publishing as Be
Mineralocorticoids
35
Produced in the middle layer of the adrenal cortex  Promote normal cell metabolism  Help resist long-term stressors  Released in response to increased blood levels of ACTH
Glucocorticoids
36
Produced in the inner layer of the adrenal cortex  Androgens (male) and some estrogen (female)
Sex hormones
37
Produces two similar hormones in adrenal medulla. Deals with short term stress
Epinephrine and Norepinephrine
38
allows glucose to cross plasma membranes into cells from beta cells
insulin
39
allows glucose to enter the blood from alpha cells
glucagon
40
Found on the third ventricle of the brain  Secretes melatonin  Helps establish the body’s wake and sleep cycles
Pineal Gland
41
Located posterior to the sternum in upper thorax  Largest in infants and children 2. Produces
Thymus 2. Thymosin
42
Produced by Graafian follicles of the ovaries or the placenta  Stimulates the development of secondary female characteristics  Matures female reproductive organs  Helps prepare the uterus to receive a fertilized egg  Helps maintain pregnancy
Estrogens
43
Produced by the corpus luteum  Acts with estrogen to bring about the menstrual cycle  Helps in the implantation of an embryo in the uterus
Progesterone
44
specialized lymphatic capillaries
Lacteals
45
collections of lymphatic tissue)
Peyer’s patches
46
saclike first part of the large intestine
Cecum
47
Accumulation of lymphatic tissue that sometimes becomes inflamed
appendix
48
Ascending  Transverse  Descending  S-shaped sigmoidal
colon
49
A clot in an unbroken blood vessel  Can be deadly in areas like the heart
Thrombus
50
 A thrombus that breaks away and floats freely in the bloodstream  Can later clog vessels in critical areas such as the brain
Embolus
51
Platelet deficiency  Even normal movements can cause bleeding from small blood vessels that require platelets for clotting
Thrombocytopenia
52
Hereditary bleeding disorder  Normal clotting factors are missing
Hemophilia
53
Injured tissues release thromboplastin  PF3 (a phospholipid) interacts with thromboplastin, blood protein clotting factors, and calcium ions to trigger a clotting cascade  Prothrombin activator converts prothrombin to thrombin (an enzyme)
Coagulation
54
Anchored platelets release serotonin  Serotonin causes blood vessel muscles to spasm  Spasms narrow the blood vessel, decreasing blood loss
Vascular Spasm
55
Collagen fibers are exposed by a break in a blood vessel  Platelets become “sticky” and cling to fibers  Anchored platelets release chemicals to attract more platelets  Platelets pile up to form a platelet plug
Platelet Plug Formation
56
regulates osmotic pressure
Albumin
57
help to stem blood loss when a blood vessel is injured
Clotting proteins
58
help protect the body from antigens
Antibodies
59
red blood cells
Erythrocytes
60
white blood cells
Leukocytes
61
cell fragments
Platelets
62
The main function is to carry oxygen
Erythrocytes
63
Iron-containing protein  Binds strongly, but reversibly, to oxygen
Hemoglobin
64
Crucial in the body’s defense against disease  These are complete cells, with a nucleus and organelles  Able to move into and out of blood vessels (diapedesis)
Leukocytes
65
Granules in their cytoplasm can be stained  Include neutrophils, eosinophils, and basophils
Granulocytes
66
Lack visible cytoplasmic granules  Include lymphocytes and monocytes
Agranulocytes
67
Multilobed nucleus with fine granules  Act as phagocytes at active sites of infection
Neutrophils
68
Large brick-red cytoplasmic granules  Found in repsonse to allergies and parasitic worms
Eosinophils
69
Have histamine-containing granules  Initiate inflammation
Basophils
70
Nucleus fills most of the cell  Play an important role in the immune response
Lymphocytes
71
Largest of the white blood cells  Function as macrophages  Important in fighting chronic infection
Monocytes
72
Derived from ruptured multinucleate cells (megakaryocytes)  Needed for the clotting process
Platelets