Lecture 15 + 16 - Anxiety Disorders Flashcards

(33 cards)

1
Q

Anxiety disorder prevalence

A
  • in a year; 12% of Canadians

- Lifetime: 1 in 4

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2
Q

Comorbidity in anxiety disorders

A
  • HIGHLY comorbid
  • treating other disorder has strong reduction of anxiety or depressive disorders (E.g. treatment of panic => improvement in Depression and GAD)
  • underlying structure of all these is negative affect
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3
Q

Cognitive therapy of anxiety

A
  • CBT and behavioural techniques
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4
Q

Social Anxiety Disorder

A
  • Hypersensitive to criticism and rejection
  • Low Self esteem, feelings of inferiority
  • Restricted vocational and social achievements
  • Prevalence 3 to 13%
  • many more people experience anxiety than meet strict criteria
  • Impairs daily life functioning

As explained by basic cognitive model:
invite to party –> think: people will judge me, i’m not interesting or attractive –> anxiety and nausea; don’t go

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5
Q

What are the different types of learning

A

1) Non-Associative Learning: habituation, sensitization
2) Associative Learning:
Classical Conditioning: Reflex-Based
Operant Conditioning: Reward-Based
3) Cognitive Learning: observational Learning

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6
Q

Operant conditioning

A
  • Reinforcement; increases likelihood of behaviour
  • Punishment; decreases likelihood of behaviour
  • Positive; giving something
  • Negative; removing something
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7
Q

Operant conditioning and social phobia

A
  • when someone avoids social situations it’s negative reinforcement
  • removing anxiety symptoms by not going out
    Other examples or negative reinforcement:
  • safety behaviors
  • Avoiding to go to social events to reduce anxiety
  • Self-harm to reduce emotional pain
  • Binge-eating/ drinking
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8
Q

Two process theory

A
  • obtain behaviours through classical conditioning

- maintain behaviours through operant conditioning

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9
Q

Properties of associative learning (operant and classical conditioning)

A
  • extinction

- stimulus generalization

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10
Q

Observational learning

A

Learning by watching others, without
instruction or reinforcement.
- Also called vicarious learning
- Watch someone else being reinforced for doing something and take cues from them

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11
Q

Exposure therapy - 3 types

A

1) Imaginal: use vivid imagery
2) Interoceptive: provocation of a feared physiological symptom (mostly applicable to panic disorder; provoke symptoms such as sweating, dizziness or short of breath)
3) In vivo: actual encountering the feared stimulus/situation

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12
Q

Issues with exposure therapy

A
  • Drop out rates high

BUT If prepare well and do it gradually the drop out rate is “normal” compared to other therapies

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13
Q

Mechanism of Change in Exposure

A
  • Habituation vs. inhibitory learning

- Fear associations are not removed, but new learning occurs, more tolerance

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14
Q

Steps of exposure therapy

A
  • Psycho-education
  • Make with client a list of situations that creates anxiety
  • Develop a fear hierarchy and pick collaboratively situations
  • Exposure, starting with those that induces moderate fear, gradually go up (use the SUDS to measure)
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15
Q

In-vivo exposure

A
  • Include situations that put the client at risk for rejection or disapproval
  • Do ensure safety
  • Can be adaptable during therapy
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16
Q

Cognitive-Behavioural Treatment Strategies

A
  • Can be a combination of cognitive strategies (evaluating/re-evaluating automatic thoughts) and exposure techniques
17
Q

Anxiety sensitivity

A
  • Cognitive perspective
  • Fear of anxiety-related symptoms based on the beliefs that these symptoms have harmful physical, psychological and/or social consequences
    • Interpreting suddenly occurring physical sensation as dangerous
    • Social concerns regarding the symptoms
  • High anxiety sensitivity predicts the development of panic disorder among soldiers in training
  • Anxiety sensitivity index (measures of anxiety sensitivity)
18
Q

Social phobia

A
  • Prevalence: 6.8%
  • M/F ratio is 1:1
  • Not clearly linked to early trauma
  • Potential genes: SLC6A4 (serotonin transporter) and COMT
  • In children: greater behavioural inhibition predicts social anxiety disorder later on
  • Fear that will act in a way that is embarrassing
  • Experience anxiety in social situations
  • Recognize that the fear is excessive
  • Avoidance or severe anxiety
  • Panic attacks common, but not unexpected (is not panic disorder because they’re specific)
  • Diagnosis is not easy**
19
Q

Social Anxiety in Childhood/Adolescence

A
  • Childhood and especially adolescent anxiety is predictive of anxiety disorder in adulthood
  • Anxiety in childhood/adolescence is predictive of less education, lower income and more stressful life events later in life
  • Predictive of mental health problems such as substance abuse and MDD
20
Q

Brain mechanisms in social anxiety/phobia

A
  • Increased bottom-up activation (ex: amygdala) and reduced top-down brain regulation (ex: dorsal PFC)
  • Reduced dopamine activity in striatum (involved in sensitivity to reward/punishment)
21
Q

Biology of anxiety disorders

A
  • Potential ntrs: dopamine, serotonin
    o Ex: reduced serotonin 1a receptor density in insula, amygdala and anterior cingulate
  • Dopamine: reduced activity in striatum
22
Q

Cognitive: self-focused attention

A
  • Attention focused externally: other person, environment, task at hand
  • Attention focused internally: own arousal, behaviour, thoughts, emotions, or appearance
  • Stroop task
    • People with social phobia slower to name social threat words, but not physical threat words
      • Criticize, blushing vs. cancer
      • Unclear if it’s specific for social phobia
23
Q

Perceived poor social skills in social anxiety disorder

A
  • Most people with SAD seem to possess adequate social skills. But they are inhibited when it comes to applying them in social situations
24
Q

Avoidance and the use of safety behaviours

A

o Safety behaviour: behaviours that are intended to reduce the distress or hide a person’s anxiety
o Similar to negative reinforcement
o SAD use often safety behaviours

25
Panic Disorder
o Disorder is recurrent, unexpected attacks o At least one month significant concern or worry or maladaptive change in behavior o Not due to substance of other disorder o Often goes with avoidance of social situations o 4.7% lifetime o Risk factors: - Female: (F:M = 2:1) - b/w ages 14-30 (average age of onset 21-23y) - History of cigarette smoking - Often life stress at or around first attack o Long-term course is unpredictable o Goes with agoraphobia - Avoidance behaviour = negative reinforcement
26
Etiology of panic disorder
Genetic Vulnerability: twin studies show concordance rates of 30-40% - Multiple genes has been linked, but inconsistent
27
False suffocation alarm theory of panic disorder
- PD patients have lower threshold for detecting CO2 - The brain's suffocation monitor incorrectly signals a lack of oxygen (relative to carbon dioxide), and thus triggers a false suffocation alarm. - This produces sudden respiratory distress followed swiftly by a brief hyperventilation, panic, and the urge to flee - Specific for Panic disorder - Effects also visible in healthy first degree relatives - Reaction to CO2 inhalation can be influenced by serotonin manipulations - Some evidence that treatment reduces the response
28
Cognitive view of panic disorder
- catastrophic misinterpretation of bodily symptoms | - treatment with CBT
29
Cognitive model of panic disorder
Entering a crowded bus, feel a bit warm --> I am going to suffocate, I cannot breath, I get crazy --> Increased sweating and other phyiological responses
30
Generalized Anxiety Disorder (GAD)
- Core feature: excessive worry, more than 6 months - Prevalence: 2.8-5 % in the population - Male/female ratio:1:2 - Highly comorbid (substance abuse, depression, other anxiety disorders) - Female: more often MDD; Men more often alcohol abuse/dependence - heritability weak - Onset childhood/adolescence --> chronic course
31
Treatment for GAD
SSRIs | CBT
32
GAD in children
- Excessive worry - Perfectionism - Excessive self-criticism - Convinced about something bad will happen - Need for reassurance/approval - Often not aware that anxiety is disproportionate (differerent than in adults)
33
Treatment STUDY on GAD for kids
- All therapies better than placebo | - Best option was combination (CBT and SSRI)