What are the two models of development for memory cells?
- Linear: memory cells arise from a factor T cells as the primary response subsides
- Branching: activated t cells give rise to daughter cells can can be effectors or memory
Where is a central memory t cell found?
found in blood, T cell zones, and lymph
Where is a effector memory t cell found?
found in non-lymph, lymph, lymph nodes, and blood
Where is a resident memory t cell found?
remain in a single tissue
memory T cells are especially sensitive to ____, to ensure…
IL-7 and IL-15; longterm survival.
True or False?
memory cells respond slower than naive cells
false
A primary immune response is made up of ____ B/T cells.
naive
A secondary immune response is made up of ____ B/T cells.
memory
what happens during a secondary immune response thats different than a primary one? how is this ensured?
(think the cells responding, and what they do).
- memory b cells function instead of naive.
- memory b cells block naive b cell activation through Fcγ-RIIBI receptor.
What are the 4 types of Innate Lymphoid cells (ILCs)? What do they stimulate?
- Cytotoxic ILC (apoplosis)
- Group 1 ILC (macrophages)
- Group 2 ILC (eosinophils, mast cells, basophils)
- Group 3 ILC (neutrophils)
Group 1 ILCs stimulate a respond using…
IFN-γ
Cytotoxic ILCs stimulate a respond using…
IFN-γ
Group 2 ILCs stimulate a respond using…
IL-13 and IL-5
Group 3 ILCs stimulate a respond using…
IL-17 and IL-22
T(h)1 stimulates…
macrophages
(fight intracellular pathogen w classical activation)
T(h)2 stimulates…
eosinophils, mast cells and basophils
(expel intestinal helminths and repair tissue)
T(h)17 stimulates…
neurophils
(enhances clearance of bacteria and fungi)
