lecture 18 and 20 brain killers Flashcards
(11 cards)
1
Q
stroke happens when
A
decreased blood flow and oxygen to the brain
2
Q
PET scan
A
inject radioactive fluid into the brain and see where the blockage is at
3
Q
core tissue
A
dead
4
Q
penumbra
A
vulnerable tissue
5
Q
what do damaged neurones release
A
toxins
neurotransmitters eg glutamate
ions eg sodium and calcium
free radicals
6
Q
reperfusion injury leads to
A
inflammation and oxidative stress
7
Q
reparative mechanisms
A
plasticity
neurogenesis angiogenesis
8
Q
inflammation leads to
A
glial cell activation and oedema
9
Q
the damaged brain will produce
A
cytokines
10
Q
interleukin 1
A
is a cytokine, an inflammatory mediator produced in the brain that mediates brain injury
11
Q
if we inhibit IL1
A
can reduce inflammation and decrease stroke
