Lecture 18: Development of Pharyngeal Arches Flashcards
What are the 3 principle components of the pharyngeal complex?
Pharyngeal arches, clefts, and pouches
Name the type of tissue that migrates from the 1st and 2nd pharyngeal arches into the developing face
Neural-crest derived mesenchyme
From which embryonic germ layer do muscles develop?
What type of cells give rise to the facial skeleton and coronal and sagittal sutures?
Neural crest cells
What gives rise to the posterior neurocranium and basicranium?
Which pharyngeal arch gives rise to Meckel’s cartilage, malleus, incus, mandible, and maxilla?
Pharyngeal arch 1
Fusion of which prominences is required for the normal development of the upper lip?
Nasomedial, nasolateral, and maxillary prominences
What facial abnormality is the result of failure of the nasomedial and maxillary prominences to fuse?
What is the problem underlying cleft palate?
Problem with nasomedial segments fusing
What are the muscular components of pharyngeal arch 1?
Muscles of mastication - temporalis, masseter, mylohyoid, anterior belly of digastric
What are the muscular components of pharyngeal arch 2?
Muscles of facial expression - buccinator, orbicularis oris, posterior belly of digastric, platysma, frontalis, orbicularis oculi, occipitalis
What are the muscular components of pharyngeal arch 3?
What are the muscular components of pharyngeal arches 4 and 6?
levator veli palatini, pharyngeal muscles, intrinsic muscles of larynx
What are the nerve components of pharyngeal arch 1?
Trigeminal nerve (CN V) - specifically mandibular division (V3)
What are the nerve components of pharyngeal arch 2?
Facial nerve (CN VII)
What are the nerve components of pharyngeal arch 3?
Glossopharyngeal nerve (CN IX)
What are the nerve components of pharyngeal arches 4 and 6?
Vagus nerve (CN X)
What structures does the frontonasal prominence form?
forehead, bridge of nose, medial/lateral nasal prominences
What structures does the maxillary prominence form?
cheeks, lateral portion of upper lip
What structures does the medial nasal prominence form?
Philtrum of upper lip, crest/tip of nose