lecture 2 Flashcards

(13 cards)

1
Q

how did Golgi visualize neurons

A

soaked and stained brains in solution

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2
Q

what are the four regions of a neuron

A
  1. soma
  2. axon and axon collaterals
  3. dendrites (spiny or smooth)
  4. pre synaptic release sites (terminals, boutons and non-localized sites)
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3
Q

what does the size of a dendrite indicate about a neuron

A
its convergence (inputs)
the territory that neutron will pay attention to
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4
Q

cell body characteristics

A

main metabolic centre of neuron- lots of. mitochondria
site of protein synthesis- lots of endoplasmic reticulum
around 8-200um

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5
Q

dendrites characteristics

A
primary sites of INPUT from other neurons 
can release Its
contains ribosomes (can make proteins)
vary in diameter
contain lots of actin
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6
Q

axon characteristics

A

specialized for relaying electrical signals (conduct AP)
vary in length but constant diameter
contain microtubules and MTBP - involved in transport
always have specialized areas to release NTs

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7
Q

how do neutrons communicate with eachother

A

synapses

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8
Q

what is a directed synapse

A

transmitter is released onto a receptor ~15nm away from the cleft
ex. axo-dendritic, axo-somatic, axo-axonic

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9
Q

what is a non directed synapse

A

transmitter is released onto a synapse many um away

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10
Q

what is 2 photon microscopy

A

Winifred denk- concept that putting in 2 red photons very fast will act the same way as 1 blue would - can use green fluorescence using red light

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11
Q

spine characteristic

A

compartmentalize biochemical processes driven by calcium

produce amplification of local voltage changes if voltage gated channels are in spine head

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12
Q

what is convergence

A

the number of inputs to a single neuron

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13
Q

what is divergence

A

number of targets innervated by one neuron

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