LECTURE 20: Neurological Diseases I Flashcards
What is avian encephalomyelitis?
AE ssRNA virus that is non-enveloped
AE is _____ only.
Chicken (young birds)
AE has what kind of transmission?
Vertical (hen to chick)
What does viremic mean? What disease causes this?
Virus in the blood
AE
What are clinical signs of AE?
Ataxia, fine tremors, drop in egg production progression to paralysis
What is the common name of AE?
Epidemic Tremor
Why do you vaccinate hens for AE?
To protect the chicks
What is the dead giveaway for AE?
Tremors of the head
What sampling will you do for AE?
- Serology
- PCR
- Virus Isolation
- Histopathology
**Brain for sampling
What does the prevention and treatment look like for AE?
NO TREATMENT
Vaccination
What is Marek’s disease?
Herpesvirus, dsDNA enveloped
What serotype of Marek’s disease is pathogenicc?
Serotype 1 (pathogenic)
What are the clinical signs of neurological mareks?
Transient paralysis
Peripheral nerve paralysis
Blindness
Depression and immunosuppression
Mareks disease effects what window age of birds?
Before 16 wks but not right away when they are young
What kinds of cells does mareks affect?
B cells and develops latency in t cells
Where is the infected virus produced in mareks?
Feather follicle epithelium (FFE)
What are the forms of neurological lesions in a mareks necropsy?
- Nerve degenerative lesions
- Nerve lymphocytic inflammation
- Swollen nerves, discoloration and loss of cross strainsn
What is a necropsy giveaway of mareks?
Huge ass nerves
What samples should you take for mareks?
- PCR
- Histopathology
How do you prevent and control mareks?
Vaccination as early as possible
What is the best vax for mareks?
Serotype 1 vaccine
What are the four necropsy lesion patterns?
- Visceral
- Cutaneous
- Ocular
- Neural
What is arbovirus?
Virus that is caused by insects
What is botulism? (limberneck)
Gram positive bacteria that causes limp neck (super resistant)
