Lecture 21 AIDS

Question 1

More than 2 Billion people have died of HIV, T/F?

Answer 1

False, you cannot die from HIV, only from its opportunistic infections

Question 2

Koch’s postulates for HIV as the cause of AIDS are?

Answer 2

1. cause associated with disease
2. pathogen can be isolated/grown out of host
3. pathogen transmits to others

Question 3

The first case of HIV was where?

Answer 3

Congo in Kinsasha

Question 4

What is the msot common form of HIV? Which one is Africa containted?

Answer 4

HIV1 most common, HIV2 west africa

Question 5

Origin of HIV1 is

Answer 5

chimpanzees

Question 6

Origiin of HIV2 is

Answer 6

sooty manganeeze monkey

Question 7

The mechanism of HIV is:

Answer 7

depletion of CD4 helper T cells, and then Ols infection happens

Question 8

Describe acute HIV phase

Answer 8

asymptomatic or flu/mono symptom, 2-8 wk, negative by antibody test, high viral load

Question 9

Describe the asymptomatic stage of HIV

Answer 9

HIV pos with detectable antibodies, years, heavy destruction of immunity/CD4

Question 10

How long is the normal progression of HIV caused AIDS? What about slow and fast

Answer 10

5-10 years, slow is 10-20 and fast is 2-3

Question 11

What type of virus is HIV?

Answer 11

retrovirus, 2 RNA molecules and lipid membrane

Question 12

What are the HIV viral proteins?

Answer 12

Pol, Gag, Env

Question 13

The early risk coreceptor for HIV is

Answer 13

CCR5 (but isn’t essential)

Question 14

A polymerase makes mistakes in HIV (drift/Shift)?

Answer 14

Shift

Question 15

Within 24 hrs, how many variations does HIV make?

Answer 15

10 Billion

Question 16

Name a 20 min HIV test with lots of false positivies

Answer 16

oroquick

Question 17

Reporting issues with HIVincluse

Answer 17

names/codes, confidentiality/anonymity, info differences btwn states

Question 18

HIV drugs include

Answer 18

CCR5 blocker, protease inhibitors, INTI etc

Question 19

HIV drugs cure HIV, T/F?

Answer 19

false, they syppress symptoms

Question 20

What can be taken before intercourse to prevet HIV?

Answer 20

PreP pill

Question 21

An unusual treatment that was historically used to treat HIV was

Answer 21

BMT

Question 22

How many ppl infected with HIV since 1980?

Answer 22

75 million

Question 23

How many people died from AIDs related illness since 1980?

Answer 23

34 million

Question 24

3/4 of subsaharan HIV infections are ___

Answer 24

girls :(

Question 25

Where are HIV #s the highest in the US?

Answer 25

Northeast and south

Question 26

Which population si most affected by HIV in the US?

Answer 26

African americans, men die more

Question 27

Women who have HIV can transmit HIV from breastfeeding T/F?

Answer 27

TRUE, so it is discouraged

Question 28

Condoms are __% effective for HIV prevention

Answer 28

60