Lecture 21 and 22 Flashcards

Hormones (45 cards)

1
Q

many hormones impact multiple tissue types and ….

A

have diverse effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

some hormones are both …. and ….

A

both catabolic and anabolic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what type of hormones tend to act faster

A

peptide and amine hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what type of hormones tend to act slower

A

steroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

in the big picture, prolonged or sustained competitive exercise will have what impact hormones

A

increase several catabolic hormones and suppress insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

in the big picture, activating many motor units tends to cause what for hormones

A

cause more anabolic hormone profile, in exercise and recovery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

are steroid hormones water soluble or insoluble

A

water insoluble

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

are peptide and amine hormones water soluble or insoluble

A

water soluble

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

when are peptide and amine hormones made

A

made in advance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how do steroid hormones work

A

steroid hormones enter cells and bind at the nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how do peptide hormones work

A

attach at the cell surface

use second messengers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are second messengers

A

intracellular compound that increases in concentration with binding of a hormone to its receptor and smplifies the cellular response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

hormones change the rates of specific reactions in target cells by changing the rates of :

A
  • transport across membrane e.g insulin
  • secretory activity e.g GHRH
  • enzyme activity e.g HSL
  • protein synthesis e.g testosterone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how does hormone concentration in blood affect the rate of secretion

A

if there is more in the circulation, this will remove the stimulus to secrete it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

hormone concentration in the blood can affect the rate of inactivation or

A

excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

hormone concentration in the blood can effect the quantity of what

A

quantity of transport protein (for steroids)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what affects hormone receptor interactions

A
  • blood hormone levels
  • number of target cell receptors
  • affinity of binding
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

at rest you have a larger …. volume and you are secreting more what into the circulation

A

at rest you have a larger plasma volume and are secreting more insulin into the circulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

in exercise there is a change in what factors that can change the cells sensitivity to hormone

A
  • change in secretion
  • change in plasma volume
  • change metabolism / clearance
  • change in receptor sensitivity
  • change in receptor density
20
Q

during rest how is the release of insulin controlled and why is this changed during exercise

A

by negative feedback, changed in exercise as exercise is a stressor

21
Q

during exercise there is greater activation of what nervous systems

22
Q

during exercise what nervous stimulation is increased on the medulla

A

SNS stimulation

23
Q

what glands are associated with catabolic or stress situations (exercsise)

A

adrenal glands = stress hormones

24
Q

what glands are associated with anabolic states (recovery)

A

gonads = sex hormones

25
what is the speed of the catecholamine response to exercise
vital , FAST response
26
what are the effects of the catecholamine response to exercise
- CV pressor responses - increased substrate mobilsation - facilitates other catabolic hormones - immune mobilisation
27
which catecholamine increases the most during the progression towards VO2 max
noradrenaline, also small increase in adrenaline
28
what is the cardiovascular effect of catecholamines
increased blood pressure and redistribution
29
what happens to the catecholamine response at a given absolute intensity after training for awhile
decreased catecholamine response at given absolute intensity
30
what happens to the catecholamine response at a given relative intensity after training for awhile
same response
31
after training for awhile what will happen to the amount of growth hormone released and why
you have an adaptation to exercise, better cardiovascular capacity, less stress and can access fuels easier so growth hormone isn't released as much after training
32
in what way does adrenaline increase with exercise intensity
increases disproportionally with exercise intensity
33
adrenaline and free calcium will increase what in the muscle
increase glycogenolysis in muscle
34
what has a massive effect on glycogen depletion
exercise intensity
35
mobilisation of free fatty acids spares what at moderate exercise intensities
spares glycogen
36
mobilisation of free fatty acids is strong in what exercise
moderate or prolonged
37
when is there less free fatty acid mobilisation during exercise
with increased CHO feeding
38
why is there a decrease in fatty acid mobilisation in heavy exercise despite strong hormonal drive for free fatty acid mobilisation
- decreased blood flow to adipose tissue - increased acidity (promotes resynthesis of triglycerides, and inhibits HSL)
39
during heavy or prolonged exercise where energy is decreased what effect will cortisol released from the adrenal cortex have
- increased free fatty acids (lipolysis) - increased amino acids (used for gluconeogenesis) - decreased glucose uptake
40
two ways that cortisol is controlled during exercise
negative feedback control feedforward control
41
insulin is anabolic and suppressed by what
suppressed by catecholamines
42
glucose uptake by muscle is what times faster in exercise
7-20x faster
43
insulin decreases during exercise, but why is glucose uptake increased during exercise
increased GLUT4 activity and increased insulin sensitivity
44
higher intensity exercise has more powerful effects on hormones but what is this response blunted by
aerobic fitness (relative intensity of exercise) CHO availability ( before and during exercise)
45
fitness allows for much reduced hormone responses to what
to same absolute exercise intensity