What is the leading cause of death by disease past infancy among children in the United States?
What is the most common types of cancer diagnosed in chidlren ages 0-14 y/o in the US?
What is the most common types of cancer diagnosed in adolescents 15-19 y/o; what is a common infectious agent implicated?
Which type of lymphoma is the most common malignancy in age group 15-19 y/o?
What are B-symptoms?
- Unexplained fever 39°C
- Wt. loss >10% total BW over 6 months
- Drenching night sweats
Any pt with persistent, unexplained LAD unassociated with an obvious underlying inflammatory or infectious process should get what?
A CXR to rule of mediastinal mass before undergoing LN biopsy
What are the clinical manifestations of Wiscott-Aldrich Syndrome; how is it inherited; what is it a risk factor for?
- X-linked recessive
- Recurrent sino-pulmonary and ear infections
- Severe atopic dermatitis
- Bleeding --> 2' to significant thrombocytopenia
- Risk factor for NHL***
Burkitt lymphoma commonly manifests in pediatric populations how?
- Abdominal (sporadic type)
- Head and neck dz (endemic type) w/ involvement of BM or CNS
Which genetic trisomy associated with both ALL and AML?
Which type of leukemia constitutes 97% of all childhood leukemias?