Lecture 3 Flashcards

1
Q

What is diffusion?

A

The spontaneous process in which material flows from a region of high concentration to low concentration.

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2
Q

Give Fick’s law, giving the rate of diffusion

A

D = Diffusion constant

Δc/Δx = ‘Concentration gradient’

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3
Q

The diffusion constant (D) is strongly dependent on…

A

Temperature

As temp. increases, so does the diffusion.

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4
Q

Diffusion constant formula

A

k = Boltzmann Constant

f = Friction Constant

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5
Q

Give the formula for Stokes’ law

(Calculate Friction Constant)

A

f = 6πRη

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6
Q

The diffusion constant for gases in air are usually…

A

Inversely proportional to the square root of the molecular mass.

(As D decreases, m increases)

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7
Q

Give Van’t Hoff Law

Can be used to calculate osmotic pressure

A
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8
Q

Isotonic Solution

A

Where osmotic pressure is equal to the reference osmotic pressure

E.g Blood

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9
Q

Hypotonic Solution

A

Where osmotic pressure is less than the reference osmotic pressure

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10
Q

Hypertonic solution

A

Where osmotic pressure is more than the reference osmotic pressure

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11
Q

Which only type of solution should be used for infusions?

A

Isotonic

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12
Q

Which piece of apparatus can be used to measure osmotic pressure?

A

Pfeffer type osmometer

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13
Q

Which formula can indirecty be used to calculate osmotic pressure?

A
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14
Q

Formula to calculate the rate of passive diffusion.

A

Aeff = Effective cross section of the pores

Δc = Concentration difference between the sides of the membrane

w = membrane thickness

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15
Q

Formula to calculate permeability.

A
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16
Q

There is a positive correlation between permeability and…

A

Lipid solubility

17
Q

Four differences between facillitated and passive diffusion.

A

Facilitated is:

Faster

Saturating

Specific

It can be inhibited

18
Q

Give the basic process of facilitated diffusion.

A

Substrate molecule transported to carrier substrate complex with carrier molecule C

This complex can move within the membrane but cannot leave it

At the other side, the substrate can leave the membrane

19
Q

Which membrane transport uses ATP against concentration gradients?

A

Active Transport