Lecture 3: mechanisms of evolution Flashcards
(14 cards)
locus
physical location in/on a chromosome
gene
a DNA sequence that encodes a product with a distinct function
allele
variant
genotype
the genetic constitution of an individual organism
HW assumptions
no migration
no natural selection
infinite population size
no mutation
random mating
mutations
the ultimate source of genetic variation
what are mutations caused by?
errors in DNA replication, mitosis, meiosis. damage to DNA
mutation rate
organisms with larger genomes tend to have higher mutation rate per bp per generation
effects of mutations
can affect an organisms fitness.
mutations that have phenotypic effects often show pleiotrpy
silent mutation
mutations with no effect on phenotype
neutral mutation
mutations with no effect on fitness
germline mutations
gametes: egg and sperm
soma mutations
all other tissues