lecture 35

Question 1

how can xenobiotics be absorbed

Answer 1

simple diffusion, simple diffusion, active tansport, endocytosis

Question 2

most important xsites for biotransformation of phytochemicals

Answer 2

liver and gut microbiota

Question 3

most prevalent active ingredient in cannabis

Answer 3

TCH

Question 4

second most prevalent active ingredient in cannabis

Answer 4

cannabiodiol (CBD)

Question 5

does CBD cause a high

Answer 5

no

Question 6

isolavones imitate

Answer 6

human estrogens
reduce menopausal symptoms and osteoporosis

Question 7

what is most like estrogen

Answer 7

equol

Question 8

where is the place with the highest phutochecmical in soybean and why

Answer 8

hypocotyl, place where there is germination

Question 9

apoptosis

Answer 9

programmed cell death triggered by release of pro-apoptotic factors

Question 10

endogenous ROS

Answer 10

enzymes
interaction of ROS with transition metals
ETC

Question 11

environmental ROS

Answer 11

cigarette smoke
pollution
surface ozone
UV irradiation

Question 12

what metals catalyze production of reactive radicals and reactive oxygen species

Answer 12

iron, copper

Question 13

what reaction produced hydroxyl radicals and how

Answer 13

ferrous iron reacts w hydrogen peroxide in a fenton reaction