Lecture 4

Question 1

Antigen

Answer 1

• Proteins that are recognized by lymphocytes

- Two types: self antigens, foreign antigens

Question 2

Presentation

Answer 2

Peptides are displayed on the surface of APC’s in a way that T cells can recognize

Question 3

Epitope

Answer 3

• Highly specific antigenic determinant

- The small fragment of an antigen protein that is recognized by a T (or B) cell

Question 4

Major Histocompatibility Complex (MHC)

Answer 4

• the protein scaffold on surface of dendritic cells that displays/presents the epitope to T-cells
• HLA (human leukocyte antigen) in humans

Question 5

APC

Answer 5

Antigen presenting cells

Question 6

TAP

Answer 6

Transporter associated with antigen presentation