lecture 4 Flashcards

1
Q

If a neurotransmitter attaches to a ligand-gated channel and creates a potential that causes the inside of the excitable cell membrane to become less negative, and this potential travels only a short distance before dying out, it is considered to be a(n)…

A

depolarizing graded potential

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2
Q

when do graded potentials arise ?

A

when ion movement causes a minor change in the resting membrane potential

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3
Q

Typically graded potentials occur in the…

A

dendrites and cell body

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4
Q

If three depolarizing graded potentials and two hyperpolarizing graded potentials occur in a dendrite at the same instant, what is the summation of their potentials equivalent to?

A

one depolarizing graded potential

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5
Q

what ion pass through the resting neuronal cell membrane most easily?

A

potassium

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6
Q

A resting nerve fiber is polarized because the concentration of

A

na+ is higher on the outside and k+ is higher on the inside

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7
Q

Voltage-gated channels participate in the generation and conduction of _____ in the axons of all types of neurons.

A

action potentials

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8
Q

What is the typical resting membrane potential of a neuron?

A

-70 mv

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9
Q

The differences in electrical charges on either side of the cell membrane results in what is referred to as

A

membrane potential

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10
Q

When the inside of the membrane becomes less negative, the membrane potential is said to be

A

depolarized

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11
Q

If the accumulation of graded potentials in the trigger zone reaches threshold, the result is

A

voltage-gated channels open

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12
Q

When a neurotransmitter attaches to a chemically-gated sodium channel, the sodium channel briefly opens to allow sodium ions to diffuse in. This action produces what type of graded potential?

A

depolarizing graded potential

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13
Q

When a neurotransmitter attaches to a chemically-gated sodium channel, the sodium channel briefly opens to allow sodium ions to diffuse in. This action produces what type of graded potential?

A

leak channels and sodium-potassium pumps

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14
Q

Na+/K+–ATPase is considered to be an electrogenic pump because

A

it contributes to the negativity of the resting membrane potential

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15
Q

When a graded potential summates to threshold at the axon hillock

A

voltage-gated na+ channels open rapidly

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16
Q

Which of these allows more potassium to exit the neuron and helps in maintaining the resting membrane potential?

A

leak channel

17
Q

During an action potential’s ___________, a second stimulus will not produce a second action potential (no matter how strong that stimulus is). This event corresponds to the period when the __________ remain open and the sodium inactivation gates have not reopened

A

absolute refractory period; voltage gated sodium channels

18
Q

During an action potential’s ___________, a second stimulus can be produced only if the stimulus is greater than the threshold stimulus. This event corresponds to the period when the __________ remain open and sodium inactivation gates have reopened.

A

relative refractory period; potassium voltage gated channels