Lecture 4- Dementia Flashcards Preview

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Flashcards in Lecture 4- Dementia Deck (20):
1

Which of the following is the strongest evidence of the patient's risk for unsafe driving?
A. Patient's self-restriction and situational avoidance
B. History of traffic citation in the past 5 years
C. Spouse's concern
D. Score of less than 24 on MMSE
E. Patient's self-rating of driving ability

C- Spouse's concern

2

Which of the following is true about risk of Alzheimer Disease?
A. Mutations in 4 known deterministic genes are associated with autosomal-dominant AD
B. The lifetime risk of developing AD in the genral population is approx. 20% assuming a life span of 75-80 years
C. AD is sporadic in approx. 75% of cases
D. Genetic risk for AD varies by race and ethnicity

C. AD is sporadic in approx 75% of cases

3

Is Dementia an inherent part of aging?

NO

4

What are the top 3 types of dementia?

1. Alzheimer Disease
2. Vascular dementia
3. Dementia with Lewy Bodies

5

Primary treatment goals with dementia

- enhance quality of life and maximize function by improving cognition, mood, and behavior

6

Treatment types for dementia

SHOULD include both pharmacologic and nonpharmacologic interventions

7

What is delerium?

Acute change in mental status
- underlying stress disorder

8

What is the ONLY type of dementia with fluctuations?

Diffuse Lewy Bodies

9

DEMENTIAS mneumonic

D- Drugs
E- Emotional disorders
M- Metabolic disorders
E- Endocrine problems
N- nutritional and neurologic disease
T- Trauma and tumor
I- Infection, Ischemia, Inflammation
A- Anemia, Arrhythmia
S- Social, Sensory, Spiritual isolation

10

Delerium

- Acute onset
- cognitive fluctuations over hours or days
- impaired consciousness and attention
- altered sleep cycles

11

Depression

- impaired concentration
- Lack of motivation, of interest, apathy
- psychomotor retardation
- sleep disturbance

12

Pharmacologic managment of dementia

- Cholinesterase inhibitors
- Memantine

13

Most common cause of dementia

Alzheimer's Disease

14

Delerium-

Acute change in mental status and always has an underlying disease

15

Diffuse Lewy-Body disease

Only dementia to show true fluctuations day-to-day

16

Frontotemporal disease

Heterogeneous group of disorders we are learning more about

17

Normo-pressure hydrocephalus

Enlargement of ventricles with fluid causing pressure on neurocircuitry around ventricles, curable with shunting if caught early enough
- abnormal gait (feet stuck to the ground), urinary incontinence, and cognitive decline

18

Overlapping Symptoms of depression and dementia

- Impaired concentration
- Lack of motivation, loss of interest, apathy
- Psychomotor retardation
- Sleep disturbance

19

DEFINITE risk factors for dementia

- age
- family history
- APOE4 allele
- Down Syndrome

20

what percentage of people over 65 have Alzheimers

6-8%