lecture 5- membrane proteins Flashcards

1
Q

membrane proteins used for

A

•transport •intracellular junction- holds membrane together •receptors •cell-cell recognition •attachment to the cytoskeleton and extracellular matrix

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2
Q

2 main functions

A

•transport of molecules across membranes •transduction of signals across membranes

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3
Q

peripheral/ extrinsic proteins

A

•on the outside of the cell- dont permeate through •they have H bonds and oletostatic •these are POLAR interactions can be disrupted by adding salt or changing the pH

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4
Q

intergral/ intrinsic Proteins

A

•interact with the hydrocarbon chain of membrane lipids that san the lipid bilayer. can only be released b agents that compete for these non-polar interactions

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5
Q

glycoproteins

A

proteins with attached carbohydrate (sugar) group. same sugars occur in both membrane glycoproteins and glycolipids. sugar on the outside of the cell is called sugar coating

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6
Q

glycocalyx

A

carbohydrates of glycoproteins and glycolipids occurs on the outer surface of plasma membranes which gives it the sugar coating

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7
Q

function of glycoproteins

A

•cell-cell recognition •cell adhesion •binding specific substrate

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8
Q

membrane proteins

A

•carbohydrate containing lipid and protein molecules are also important in cell-cell recognition

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9
Q

structure of membranes

A

•phospholipids suspended in water- bilayer

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10
Q

membrane fluidity

A

•controlled by fatty aids and cholesterol •the more the unsaturation o fatty acyl chain the more fluid •increasing the amount of cholesterol makes the membrane less fluid

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11
Q

features of membrane

A

•1:4 or 4:1 lipid to proteins •membrane lipids are hydrophilic or hydrophobic form bilayers and barriers •separates cell content from enviro •recognition and response •cell adhesion

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