Lecture 5.2 - Neurological Conditions Flashcards
What things are assessed in the pediatric neurological assessment?
LoC
Posture & Tone
Pupil Reaction
Systemic effects of neuro failure - resp + cardio
What percent of an infant’s and adult’s body weight does the brain take up?
12% - infant
2% - adult
What percent of brain growth occurs in the first 1 and 6 years of a child’s life?
50% growth by 1 year
90% by age 6
How much CSF does an infant vs an adult have?
50 mls - infant
150 mls - adult
How much of cardiac output and oxygen does the brain use?
Receives 17% of cardiac output and uses 20% of body oxygen
How is the cerebral perfusion pressure calculated?
CPP = MAP - ICP
How is orientation assessed on a modified GCS for children under 2?
Smiles, listens, follows
–> Followed by cries, persistent cry, agitated, or no response
Why is motor control limited in neonates?
Peripheral nerves are not completely myelinated at birth
How is cerebral perfusion pressure autoregulated?
Cerebral arteries change diameter in response to changes in CPP to allow for steady blood flow to the brain despite changes in MAP or perfusion
What are some metabolic regulatory mechanisms for cerebral blood flow?
Low O2 or high CO2 can cause vasodilation of cerebral arterioles to increase blood flow to the brain
Fever increases metabolic activity and production of waste products - vasodilation will promote flushing of metabolites
Why does fever result in vasodilation of the cerebral arterioles?
Vasodilation will promote flushing of metabolites
Fever —> Higher metabolic rate –> Faster production of metabolites
What is a primary concern for a child under 3mo with a fever?
Infection becoming systemic
–> Sepsis –> Meningitis
What things are tested for in a full sepsis workup?
Urine, blood, CSF
Why are infants under 3 months more susceptible to meningitis?
Immature BBB + immune system
How does the brain compensate for increase ICP?
By decreasing CSF and venous volume to make space for the mass
–> Once compensatory mechanisms are exhausted, ICP rises quickly
An infant presents with bulging fontanels, a separation of cranial sutures, increased head circumference, distended scalp veins, and a high-pitched cry, and sunset eyes.
What are these indicative of?
Increased ICP
–> Also see poor feeding & vomiting, altered LoC
A child presents with N&V, altered LoC, headache, diplopia/blurring of vision, behavioural changes and slurred speech.
What might be wrong?
Increased ICP
–> seizures can also be seen
What are some late signs of increased intracranial pressure?
Altered pupil size and reactivity
Decreased motor or sensory response
Coma
Posturing (decerebrate/decorticate)
Papilledema
Projective vomiting
Absent gag reflex
Absent gag reflex is a late sign of what?
Increased intracranial pressure
What changes in VS are a late signs of increased intracranial pressure?
Bradycardia
HTN
Irregular or decreased respirations
–> Cheyne Stokes
What are sunset eyes? What are they a sign of?
whites of eyes visible above iris/pupil
–> Sign of increased intracranial pressure in infant
How does decrease HR and RR with increased intracranial pressure exacerbate the problem and lead to decompensation?
Leads to decreased O2, increased CO2 –> cerebral vasodilation –> increased ICP –> Further decrease in RR
How does the increase in temperature (or temperature instability) or seizures lead to an increased intracranial pressure lead to neurological decompensation?
Increased metabolic needs of brain –> increased ICP –> seizures –> Increased metabolic rate
How would you assess limb weakness in a baby?
Loss of flexion tone