Lecture 6 Flashcards

(51 cards)

1
Q

Define somatic sensation

A

Sensation from body tissues

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2
Q

Define somatic sensation

A

Sensation from body tissues

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3
Q

What does fibre Aalpha sense?

A

Motor and somatic proprioception

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4
Q

What do Abeta nerve fibres sense?

A

Touch pressure

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5
Q

What do Adelta nerve fibres sense?

A

Pain and temperature

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6
Q

What do Agamma nerve fibres sense?

A

Motor spindles

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7
Q

What do B nerves do?

A

they are pregangionic sympathetic neurons

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8
Q

What do C fibres sense?

A

Pain and they are the post-ganglionic sympathetic neurons

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9
Q

Which type of nerve fibre is responsible for touch pressure?

A

Abeta (II)

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10
Q

Which type of nerve fibre is responsible for motor and somatic proprioception?

A

A alpha (I)

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11
Q

Which type of nerve fibre is responsible for pain and temperature?

A

A delta (III)

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12
Q

Which type of nerve fibre is responsible for motor spindles?

A

A gamma

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13
Q

Which type of nerve fibre is pre-ganglionic sympathetic?

A

B

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14
Q

Which type of nerve fibre is responsible for pain and is post-ganglionic sympathetic?

A

C (IV)

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15
Q

Which type of nerve fibre is unmyelinated?

A

C

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16
Q

Why are there 2 sets of pain fibres?

A

A delta mediates sinal reflexes such as the withdrawal reflex
C nerves become more sensitive when the tissue is damaged

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17
Q

What neurons are involved in skin innervation?

A

Meissner’s corpuscle detects steady pressure
Bare nerve ending detects pain
Pacininian corpuscle detects vibration
Merkel’s receptor detects pressure

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18
Q

What is the threshold for cold pain and which nerve fibre detects it?

A
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19
Q

What is the threshold for hot pain and which nerve fibre detects it?

A

> 46C if held and type C

>52C would to reflexively pulling away and both type C and Adelta

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20
Q

Give an example of a rapidly adapting neuron

A

Pacinian corpuscle

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21
Q

Give an example of a slowly adapting corpuscle

22
Q

What do prostaglandins mediate?

A

Primary hyperalgesia

23
Q

List some common inflammatory mediators

A
Prostaglandins
Bradykinin
5-HT receptor
Histamine
Purines
Neuropeptides
24
Q

What are the main sources of inflammatory mediators?

A

Leukocytes

Mast cells release histamine

25
What are the main sources of inflammatory mediators?
Leukocytes | Mast cells release histamine
26
What does fibre Aalpha sense?
Motor and somatic proprioception
27
What do Abeta nerve fibres sense?
Touch pressure
28
What do Adelta nerve fibres sense?
Pain and temperature
29
What do Agamma nerve fibres sense?
Motor spindles
30
What do B nerves do?
they are pregangionic sympathetic neurons
31
What do C fibres sense?
Pain and they are the post-ganglionic sympathetic neurons
32
Which type of nerve fibre is responsible for touch pressure?
Abeta (II)
33
Which type of nerve fibre is responsible for motor and somatic proprioception?
A alpha (I)
34
Which type of nerve fibre is responsible for pain and temperature?
A delta (III)
35
Which type of nerve fibre is responsible for motor spindles?
A gamma
36
Which type of nerve fibre is pre-ganglionic sympathetic?
B
37
Which type of nerve fibre is responsible for pain and is post-ganglionic sympathetic?
C (IV)
38
Which type of nerve fibre is unmyelinated?
C
39
Why are there 2 sets of pain fibres?
A delta mediates sinal reflexes such as the withdrawal reflex C nerves become more sensitive when the tissue is damaged
40
What neurons are involved in skin innervation?
Meissner's corpuscle detects steady pressure Bare nerve ending detects pain Pacininian corpuscle detects vibration Merkel's receptor detects pressure
41
What is the threshold for cold pain and which nerve fibre detects it?
42
What is the threshold for hot pain and which nerve fibre detects it?
>46C if held and type C | >52C would to reflexively pulling away and both type C and Adelta
43
Give an example of a rapidly adapting neuron
Pacinian corpuscle
44
Give an example of a slowly adapting corpuscle
Merkel Cell
45
What do prostaglandins mediate?
Primary hyperalgesia
46
List some common inflammatory mediators
``` Prostaglandins Bradykinin 5-HT receptor Histamine Purines Neuropeptides ```
47
Which receptors detect thermal pain?
TRPV1 - Aching | TRPV2 - Reflex
48
What are the main sources of inflammatory mediators?
Leukocytes | Mast cells release histamine
49
What are the two roles of prostaglandins?
Senstitisation e.g. PGE2 | Excitation e.g. PGI2
50
What are NSAIDs?
Non-steroidal anti-inflammatory drugs e.g. ibruprofen and voltarol which work by inhibiting Cox-1 and Cox-2
51
What are the 5 spinal regions?
``` Cervical Region 8 segments Thoracic Region 12 segments Lumbar Region 5 segments Sacral Region 5 segments Coccygeal 3 segments ```