Lecture 6 - Dermatology 3 Flashcards

(49 cards)

1
Q

3 types of lice

A

Pediculus = Head and body….2-3mm in size
Phthirus = Crabs = 1mm size

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2
Q

symptoms of lice

A

inflammation and itching
presence of peppery flecks
macular swellings

behind ear good area to look

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3
Q

Lice treatment

A

topical pediculicides are typically preferred

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4
Q

1st line lice Treatment

A

Pyrethrin 0.33% and Permethrin 1%
0.33% > 2yrs, 1% > 2 months
about same cost

put into hair, let sit for about 10 min, remove with special comb

reapply in 7-10 days

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5
Q

2nd line lice treatments

A

topical prescription meds if fail/dont respond to 1st line
typically use Malathion

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6
Q

Malathion 0.5% lotion info

A

apply to dry hair, let air dry and wash off
usually 1 treatment enough, can repeat in 9 days
CI < 24 months old and dont use P.pubis

** Flammable until dry and malodorous **

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7
Q

Benzyl alcohol 5% lotion info

A

can use in infants 6 months or older who OTC dont work
applied to dry hair, rinsed after 10min and repeated after 7 days***

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8
Q

Is permethrin 5% more effective than 1%?

A

nah if failed 1% then probs fail 5%

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9
Q

Spinosad 0.9% suspension info

A

more effective than permethrin
apply to dry hair, rinse after 10min, repeat 7 days if live lice seen
Dont need to Nit comb, but recommended

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10
Q

Ivermectin 0.5% lotion info

A

can use > 6 months or older
apply, and rinse after 10min, single app

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11
Q

Why is Lindane 1% not recommended

A

Adverse drug events

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12
Q

Abametapir (Xeglyze) Lotion info

A

approved for those older than 6 months

apply, rinse after 10min

Can use shampoo anytime after treatment**
more risk of contact dermatitis

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13
Q

Oral lice treatments

A

Bactrim or Ivermectin

Bactrim: CI < 2months, preg/nursing, sulfa allergy
Ivermectin: 1 time dose

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14
Q

Non-pharm lice treatments

A

Petroleum jelly = massage int hair and left overnight, shampoo next morning…repeat 1 week

Cetaphil lotion = apply to hair, dry with hairdryer, leave overnight and shampoo morning, QW X 3wks

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15
Q

Lice exclusion for self-care w/ OTC

A

Hypersensitivity to chrysanthemums, ragweed, pediculicide ingredients
Presence of 2ndary skin infection
Presence of active tumor
2 previous unsuccessful treatment attempts
< 2yrs of age
Lice infestation of eyebrows/eyelid
Pregnancy/breast feeding

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16
Q

Lice counseling points

A

Treat other members
clean all bedding/clothing and high-heat drying
non-washable can be dry-cleaned of sealed bag for few weeks
vacuum
disinfect combs/brushes
teach children to avoid head-to-head contact

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17
Q

Factors that can affect acne

A

Hormone abnormalities or malfunctions
Physical occlusion or damage
Meds

other - Genetics, Climate, Diet, Excessive Sweating

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18
Q

Exclusions to Acne treatment

A

pts w/severe acne Type 3-4
Drug-induced acne
Possibility that its not acne
Acne persists or develops >30yrs old
No improvement after treatment attempt or 6 weeks

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19
Q

Non-pharm acne treatments

A

stress reduction
avoid extreme temps
use nondrying cleansing agents, dont want dry skin
can try comedones extractors

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20
Q

goals of acne therapy

A

reduce excess oil
control bacteria associated with acne
reduce effects of hyperkeratinization
unclog pores

21
Q

what to use on Oily to normal skin?

A

Gels and solutions

22
Q

what to use on normal skin?

A

Gels, solutions, lotions and creams

23
Q

What to use on Normal to dry skin?

A

Lotion and Creams

24
Q

Benzoyl peroxide info

A

no resistance reported
effects seen in ~5 days
comes in bunch of formulations
Fair or moist skin highest risk of irritation
can bleach or discolor fabrics

25
Salicylic acid info
repeated use can lead to salicylism CI in pt who used isotrentinoin within last 6 months
26
Retinoid CI and Warnings
CI in retinoid hypersensitivity avoided in women who are pregnant or breastfeeding avoid pts with photosensitivity disorder or eczema safety not established < 12yrs old use limited by side effects
27
If patients has Fish allergy can you use Retin-A micro?
Nah
28
Tretinoin lotion info
patients > 9yrs older Caution: fish allergy use sunscreen and protective clothing
29
Adapalene info
good option for sensitive skin OTC
30
Tazarotene info
more effective than other retinoids but more irritating Pro drug and synthetic retinoid
31
Topical retinoid general info
takes few weeks to see effect, much longer then benzoyl peroxide
32
Dapsone info
used in females w/ inflammatory acne localized discoloration of skin or facial hair * ADR*
33
Clindamcin info
preferred macrolide BPO increases efficacy * Diarrhea and pseudomembranous colitis can occur from topical use*
34
Why don't use Erythromycin topical alone?
higher risk for resistance
35
Amzeeq info
approved for 9yrs or older used for moderate to severe acne used once daily, 1hr before bed $$$$
36
Azelaic Acid
useful for noninflammatory and inflammatory acne can improve acne-induced post-inflammatory hyperpigmentation not clinically efficacious in treatment of acne
37
Acne tetracyclines
Doxy and minocycline used in moderate to severe who haven't responded Limitations: GI upset, photosensitivity, superinfections, hepatotoxicity, intracranial hypertension = rare ** don't combine with systemic retinoid **
38
when are macrolides used in acne?
usually pts who have intolerance or resistant strains to tetracycline higher rates of bacterial resistance
39
When are oral contraceptives used for acne?
usually when also want to use for contraception Net effect is an anti androgen effect additional option to give to women taking isotrentinoin
40
Spironolactone for acne
pts who haven't responded not approved by FDA as anti-androgen agent can safely use with OCs
41
Isotretinoin info
iPLEDGE program highly effective use for 15-20wks, then atleast 2 month break Reserved for severe acne or other forms that have failed treatment
42
iPLEGE requirement
females of childbearing age be on 2 forms of BC, 1 month before/after/during treatment females must have negative pregnancy tests conferred by lab monthly during, 1 month after treatment pts must access iPLEDGE monthly to document what 2 forms of birth control have been used
43
Primary forms of birth contorl
Tying tubes Vasectomy of partner IUD hormones
44
Secondary forms of birth control
Latex condom Diaphragm Cervical cap Vag sponge
45
Other iPLEDGE requirements
Males also have to register only registered pharmacy can dispense have to have yellow approval sticker on RX can only do 30 DS, no refills
46
1st choice mild acne
Topical retinoid or BPO or combo
47
1st choice moderate acne
Topical combo BPO + Topical antimicrobial....can also consider adding oral
48
1st choice severe acne
Oral antibiotic + topical combo therapy....oral isotretinoin is last line
49
acne monitoring
6-8 weeks look for results treatment can last for 20 weeks before full results are seen