lecture 7 biliary and pancreatic pathology Flashcards
(52 cards)
where does bile come from
hepatocytes
where is bile stored
gall bladder
what does eating stimulate
CCK
what does CCk secretion induce
bile release
how does the bile enter the bowel
ampulla of vater
what is the bile for
emulsification of fat
where is ile reabsorbed
terminal ileum
where is the gallbladder found
visceral surface
between right lobe and quadratic lobe
how are bile salts reabsorbed
active transport
how are bile salts returned to the liver
enterohepatic circulation
bile contains
bile acids
bilirubin
function of bile
absorbing fats
eliminate waste products
signalling molecules
what are the waste products bile helps to eliminate
excess cholesterol, bilirubin, non water soluble xenobiotics
what are the signalling molecules bile helps with
Activate MAPK pathway, ligands for receptor TGR5, activate hormone receptors
where is bilirubin conjugated
liver
what happens to the iron and globin from the RBC
recycled
where does the bilirubin go
excreted into bile then small intestine and travels to the large intestine
what happens to bilirubin in the large bowel
bacteria convert it to urobilligen
3 pathways of urobilligen
reabsorbed into blood
converted to urobilin and excreted in urine
converted to stercobillin and excreted in poo
jaudice patients wee
dark
jaundice patients poo
light
what is jaundice
high billirubin in the blood
what can occur with jaundice
pruritus - itching
where might you look for jaundice
conjuctiva
