Lecture 7 Skin and Systemic Disease Flashcards Preview

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Flashcards in Lecture 7 Skin and Systemic Disease Deck (11)
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1

Name skin conditions related to GI genetic diseases

 Hereditary haemorrhagic telangiectasia
 Blue rubber bleb naevus- develop anaemia from chronic GI bleeding

2

Name skin conditions related to GI inflammatory/autoimmune diseases

• Erythema nodosum
• Pyoderma gangrenosum

3

Vitamin deficiency can lead to__

Scurvy/Beriberi

4

Name skin conditions related to diabetes

Acanthosis Nigricans
Diabetic bullae
Diabetic dermopathy
Eruptive xanthomas
Necrobiosis lipodica

5

Name skin conditions related to hyperthyroidism

• Thyroid acropachy- thickening of the extremities and it is manifested by a triad of signs: digital clubbing, soft tissue swelling of the hands and feet, and periosteal new bone formation

6

Name conditions associated with hypothyroidism

• Pre-tibial Myxoedema

7

Name autoimmune skin conditions

Cutaneous lupus
Cutaneous vasculitis
Alopecia
Vitiligo

8

Name skin conditions that would suggest an underlying malignancy

Carcinoid syndrome
Ectopic ACTH syndrome
Paget's
Extra-mammary Paget's
Paraneoplastic Pemphigus
Acquired Hypertrichosis Lanuginosa
Bazex Syndrome
Leser-Trelat

9

Conditions associated with cancer

Acanthosis Nigricans
Dematomyositis

10

Name conditions that may be associated with malignancy

• Bullous pemphgoid
• Sweets Syndrome- very rare inflammatory skin condition characterized by a sudden onset of fever and painful rash on the arms, legs, trunk, face, or neck
• Pyoderma gangrenosum
• Acquired ichthyosis
• Cryoglobulinaemia

11

Name genetic tumour syndromes

• Peutz-Jeghers (d/d- HHT): melanosis, colon hamartomas, colon ca
• Muir-Torre: sebaceous tumours, keratoacanthomas, GI, breast, GU
• Neurofibromatosis: Café au lait, Ax freckles, Neurofibromas, nerve sheath, phaeoCCyT, carcinoid
• MEN syndromes: angiofibromas, neuromas, lichen or macular amyloid (MEN2), endocrine, P’s
• Howel-Evans: palmoplantar keratoderma, oesophageal